Evidence map›Paper›PMID 30365449›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2018

Brief Report: Age-Disparate Relationships and HIV Prevalence Among Never Married Women in Rakai, Uganda.

George Mwinnyaa, Ronald H Gray, Mary K Grabowski, Joseph Ssekasanvu, Anthony Ndyanabo, Robert Ssekubugu, Joseph Kagaayi, Godfrey Kigozi, Gertrude Nakigozi, David M Serwadda and 1 more

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Sexual partnership concurrency and age disparities associated with sexually transmitted infection and risk behavior in rural communities in Kenya and Uganda.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

George MwinnyaaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Ronald H GrayDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Mary K GrabowskiDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
Joseph SsekasanvuDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Anthony NdyanaboRakai Health Sciences Program, Kalisizo, Uganda.
Robert SsekubuguRakai Health Sciences Program, Kalisizo, Uganda.
Joseph KagaayiRakai Health Sciences Program, Kalisizo, Uganda.
Godfrey KigoziRakai Health Sciences Program, Kalisizo, Uganda.
Gertrude NakigoziRakai Health Sciences Program, Kalisizo, Uganda.
David M SerwaddaRakai Health Sciences Program, Kalisizo, Uganda.
Oliver LaeyendeckerLaboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
International Studies of the Acquired Immune Deficiency Syndrome (AIDS)ZIAAI000361 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI REDD, ANDREW · 2009 to 2025
$15.8M
Circumcision: HIV/STIs and behaviors in a RCT and post-RCT surveillance; RakaiU01AI075115 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GRAY, RONALD H · 2007 to 2011
$9.3M
ARV effects on HIV epidemiology &behaviors Rakai UgandaR01HD050180 · NICHD · JOHNS HOPKINS UNIVERSITY · PI WAWER, MARIA J · 2005 to 2009
$7.8M
Methods for Reducing Spatial Uncertainty and Bias in Disease SurveillanceR01AI102939 · NIAID · JOHNS HOPKINS UNIVERSITY · PI LESSLER, JUSTIN · 2013 to 2017
$4.6M
Enhanced Provision of Male Circumcision for HIV Prevention, Rakai, UgandaU01AI100031 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GRAY, RONALD H · 2012 to 2014
$3.2M
CHWs, mHealth, and Combination HIV Prevention in a Hotspot: A Randomized TrialR01MH107275 · NIMH · JOHNS HOPKINS UNIVERSITY · PI CHANG, LARRY WILLIAM · 2015 to 2019
$2.7M
HIV Incidence, Transmission Dynamics and Combination HIV Prevention: Rakai UgandaR01AI110324 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GRAY, RONALD H · 2014 to 2016
$2.4M
The Problem With Male Sexual/Repro Health:Qualitative/Quantitative Study, UgandaR01HD070769 · NICHD · JOHNS HOPKINS UNIVERSITY · PI WAWER, MARIA J · 2011 to 2013
$1.4M
Revealing women's hidden role as critical components of HIV transmission networks in Rakai, Uganda: an interdisciplinary approachK01AI125086 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GRABOWSKI, MARY KATHRYN · 2016 to 2020
$638k
Intramural NIH HHS Z99 AI999999NIAID NIH HHS K01 AI125086NIAID NIH HHS P30 AI094189NIAID NIH HHS R01 AI102939NIAID NIH HHS R01 AI110324NIAID NIH HHS U01 AI075115NIAID NIH HHS U01 AI100031NICHD NIH HHS R01 HD050180NICHD NIH HHS R01 HD070769NIMH NIH HHS R01 MH107275
6 · The paper itself

Abstract

backgroundAge-disparate relationships are associated with increased HIV prevalence. We determined whether the frequency of age-disparate relationships in never married women changed over time and whether they are associated with HIV prevalence in Rakai, Uganda.

methodsA total of 10,061 never married women, aged 15-49 years, in the Rakai Community Cohort Study provided information on the age of their male sexual partners from 1997 to 2013. Logistic regression was used to assess trends in age-disparate relationships (≥5 years) between never married women and their male partners. Log-binomial regression was used to estimate adjusted prevalence ratios (adjPR) of HIV prevalence associated with age-disparate relationships.

resultsTwo thousand nine hundred ninety-nine women (30%) had a male partner ≥5 years older, which remained stable over time. The prevalence of HIV among women in age-disparate relationships was 14%, 10% for women in relationships with men 0-4 years older (adjPR 1.36, 95% confidence interval: 1.22 to 1.53) not controlling women's age; however, after age adjustment, the impact of age-disparate relationships on HIV prevalence was attenuated. Age-disparate relationships were associated with increased HIV prevalence among women aged 15-17 years (adjPR 1.83, 95% confidence interval: 1.10 to 3.17), but not in other age groups.

conclusionsThe frequency of age-disparate relationships among never married women was unchanged over a 15-year period in Rakai, Uganda. Age-disparate relationships were associated with increased HIV prevalence among adolescents aged 15-17 years, but not older women.

Indexed as

Sexual PartnersSingle PersonAdolescentAdultCohort StudiesFemaleHIV InfectionsHumansMiddle AgedPrevalenceUgandaYoung Adult

Identifiers

PMID30365449
PMCPMC6205753

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.