Evidence map›Paper›PMID 30365391›Full record

ArticleAmerican journal of respiratory and critical care medicine2019

Why Is ORMDL3 on Chromosome 17q21 Highly Linked to Asthma?

Marina Miller, David H Broide

Abstract readComment
In one paragraph

Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Asthma Susceptibility GeneAmerican journal of respiratory cell and molecular biology · 2022
    Article
  5. Review
  6. Mapping the 17q12-21.1 Locus for Variants Associated with Early-Onset Asthma in African Americans.American journal of respiratory and critical care medicine · 2021
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Marina Miller1 Department of Medicine University of California San Diego La Jolla, California.
David H Broide1 Department of Medicine University of California San Diego La Jolla, California.
University of California San Diego · US

Funding

TRM and airway inflammation and remodelingU19AI070535 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BROIDE, DAVID H · 2006 to 2025
$34.2M
Chromosome 17q, allergic inflammation, and remodelingR01AI107779 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BROIDE, DAVID H · 2013 to 2024
$4.7M
GSDMB and mucosal allergic responseR01AI124236 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BROIDE, DAVID H · 2017 to 2020
$2.4M
NIAID NIH HHS R01 AI107779NIAID NIH HHS R01 AI124236NIAID NIH HHS U19 AI070535
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AsthmaChromosomesGenetic Predisposition to DiseaseHumansInflammationMembrane ProteinsPolymorphism, Single NucleotideMembrane ProteinsORMDL3 protein, human

Identifiers

PMID30365391
PMCPMC6376625
OpenAlexW2898329309

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.