Evidence map›Paper›PMID 30364959›Full record

ReviewNucleic acids research2019

FlyBase 2.0: the next generation.

Jim Thurmond, Joshua L Goodman, Victor B Strelets, Helen Attrill, L Sian Gramates, Steven J Marygold, Beverley B Matthews, Gillian Millburn, Giulia Antonazzo, Vitor Trovisco and 3 more

Abstract readReview
In one paragraph

Review in Nucleic acids research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 458 papers.

0numbers the graph read from it
0cells of the map it votes in
458citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

458 citing papers in PubMed.

  1. Article
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  4. eLife · 2026
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  19. Retention of a singlebioRxiv : the preprint server for biology · 2025
    Article
  20. Article

398 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jim ThurmondDepartment of Biology, Indiana University, Bloomington, IN 47408, USA.
Joshua L GoodmanDepartment of Biology, Indiana University, Bloomington, IN 47408, USA.
Victor B StreletsDepartment of Biology, Indiana University, Bloomington, IN 47408, USA.
Helen AttrillDepartment of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.
L Sian GramatesThe Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.
Steven J MarygoldDepartment of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.
Beverley B MatthewsThe Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.
Gillian MillburnDepartment of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.
Giulia AntonazzoDepartment of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.
Vitor TroviscoDepartment of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK.
Thomas C KaufmanDepartment of Biology, Indiana University, Bloomington, IN 47408, USA.
Brian R CalviDepartment of Biology, Indiana University, Bloomington, IN 47408, USA.
FlyBase Consortium

Funding

Resource Project CoreU41HG000739 · NHGRI · HARVARD UNIVERSITY · PI PERRIMON, NORBERT · 2014 to 2022
$32.3M
Medical Research Council MR/N030117/1NHGRI NIH HHS U41 HG000739
6 · The paper itself

Abstract

FlyBase (flybase.org) is a knowledge base that supports the community of researchers that use the fruit fly, Drosophila melanogaster, as a model organism. The FlyBase team curates and organizes a diverse array of genetic, molecular, genomic, and developmental information about Drosophila. At the beginning of 2018, 'FlyBase 2.0' was released with a significantly improved user interface and new tools. Among these important changes are a new organization of search results into interactive lists or tables (hitlists), enhanced reference lists, and new protein domain graphics. An important new data class called 'experimental tools' consolidates information on useful fly strains and other resources related to a specific gene, which significantly enhances the ability of the Drosophila researcher to design and carry out experiments. With the release of FlyBase 2.0, there has also been a restructuring of backend architecture and a continued development of application programming interfaces (APIs) for programmatic access to FlyBase data. In this review, we describe these major new features and functionalities of the FlyBase 2.0 site and how they support the use of Drosophila as a model organism for biological discovery and translational research.

Indexed as

Databases, GeneticGenomicsAnimalsDrosophila melanogasterGenome, InsectProtein DomainsSoftware

Identifiers

PMID30364959
PMCPMC6323960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.