ArticleCerebral cortex (New York, N.Y. : 1991)2019
Use-Dependent Plasticity in Human Primary Motor Hand Area: Synergistic Interplay Between Training and Immobilization.
Article in Cerebral cortex (New York, N.Y. : 1991), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06381726 (Personalized Rendering of Motor System Functional Plasticity Potential to Improve Glioma Resection and Quality of Life), which is not on this map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Personalized Rendering of Motor System Functional Plasticity Potential to Improve Glioma Resection and Quality of Life
Who cites it
21 citing papers in PubMed.
- On the Relation Between the Interstimulus Intervals and Multi-Muscle nTMS Motor Mapping.Brain topography · 2025Article
- Comparison of characteristics of bimanual coordinated movements in older adults with frailty, pre-frailty, and robust health.Frontiers in aging · 2025Article
- Effects of glabellar botulinum toxin injections on resting-state functional connectivity in borderline personality disorder.European archives of psychiatry and clinical neuroscience · 2024Article
- Overlap in the cortical representation of hand and forearm muscles as assessed by navigated TMS.Neuroimage. Reports · 2023Article
- Mapping Brain Motor Functions Using Transcranial Magnetic Stimulation with a Volume Conductor Model and Electrophysiological Experiments.Brain sciences · 2023Article
- Phantom limb therapy improves cortical efficiency of the sensorimotor network in a targeted muscle reinnervation amputee: a case report.Frontiers in neuroscience · 2023Article
- Multi-scale and cross-dimensional TMS mapping: A proof of principle in patients with Parkinson's disease and deep brain stimulation.Frontiers in neuroscience · 2023Article
- Transcranial magnetic stimulation of the brain: What is stimulated? - A consensus and critical position paper.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2022Review
- Home intervention for children and adolescents with unilateral trans-radial and partial carpal reduction deficiencies.Scientific reports · 2022Article
- Forearm and Hand Muscles Exhibit High Coactivation and Overlapping of Cortical Motor Representations.Brain topography · 2022Article
- No evidence for a difference in lateralization and distinctiveness level of transcranial magnetic stimulation-derived cortical motor representations over the adult lifespan.Frontiers in aging neuroscience · 2022Article
- Use-dependent corticospinal excitability is associated with resilience and physical performance during simulated military operational stress.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Mapping of multiple muscles with transcranial magnetic stimulation: absolute and relative test-retest reliability.Human brain mapping · 2021Article
- The Myelin Content of the Human Precentral Hand Knob Reflects Interindividual Differences in Manual Motor Control at the Physiological and Behavioral Level.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Use-Dependent Prosthesis Training Strengthens Contralateral Hemodynamic Brain Responses in a Young Adult With Upper Limb Reduction Deficiency: A Case Report.Frontiers in neuroscience · 2021Article
- Multimodal Assessment of Precentral Anodal TDCS: Individual Rise in Supplementary Motor Activity Scales With Increase in Corticospinal Excitability.Frontiers in human neuroscience · 2021Article
- Long-term motor skill training with individually adjusted progressive difficulty enhances learning and promotes corticospinal plasticity.Scientific reports · 2020Article
- Alterations of hand sensorimotor function and cortical motor representations over the adult lifespan.Aging · 2020Article
- Haptic Adaptive Feedback to Promote Motor Learning With a Robotic Ankle Exoskeleton Integrated With a Video Game.Frontiers in bioengineering and biotechnology · 2020Article
- Optimization of the Navigated TMS Mapping Algorithm for Accurate Estimation of Cortical Muscle Representation Characteristics.Brain sciences · 2019Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Training and immobilization are powerful drivers of use-dependent plasticity in human primary motor hand area (M1HAND). In young right-handed volunteers, corticomotor representations of the left first dorsal interosseus and abductor digiti minimi muscles were mapped with neuronavigated transcranial magnetic stimulation (TMS) to elucidate how finger-specific training and immobilization interact within M1HAND. A first group of volunteers trained to track a moving target on a smartphone with the left index or little finger for one week. Linear sulcus shape-informed TMS mapping revealed that the tracking skill acquired with the trained finger was transferred to the nontrained finger of the same hand. The cortical representations of the trained and nontrained finger muscle converged in proportion with skill transfer. In a second group, the index or little finger were immobilized for one week. Immobilization alone attenuated the corticomotor representation and pre-existing tracking skill of the immobilized finger. In a third group, the detrimental effects of finger immobilization were blocked by concurrent training of the nonimmobilized finger. Conversely, immobilization of the nontrained fingers accelerated learning in the adjacent trained finger during the first 2 days of training. Together, the results provide novel insight into use-dependent cortical plasticity, revealing synergistic rather than competitive interaction patterns within M1HAND.
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