Evidence map›Paper›PMID 30364895›Full record

ArticleNeuropsychiatry2018

Altered Cd8+ T lymphocyte Response Triggered by Arginase 1: Implication for Fatigue Intensification during Localized Radiation Therapy in Prostate Cancer Patients.

Leorey N Saligan, Nada Lukkahatai, Zhang-Jin Zhang, Chi Wai Cheung, Xiao-Min Wang

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuropsychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Diagnostic predictive models for cancer-related fatigue: current evidence and future directions.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Cancer related fatigue in prostate cancer.Translational andrology and urology · 2019
    Article
  9. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Leorey N SaliganNursing Research, Division of Intramural Research, National Institutes of Health, Bethesda, MD, 20892, USA.
Nada LukkahataiSchool of Nursing, Johns Hopkins University, 525 North Wolfe Street, Baltimore, MD 21205 USA.
Zhang-Jin ZhangSchool of Chinese Medicine, LKS Faculty of Medicine, the University of Hong Kong, Hong Kong.
Chi Wai CheungLaboratory and Clinical research Institute for Pain, the University of Hong Kong, Hong Kong.
Xiao-Min WangLaboratory and Clinical research Institute for Pain, the University of Hong Kong, Hong Kong.
Chinese University of Hong Kong · CNJohns Hopkins University · USNational Institutes of Health · US

Funding

Intramural NIH HHS Z99 NR999999
6 · The paper itself

Abstract

Fatigue, the most common side effect of cancer treatments, is observed to intensify during external-beam radiation therapy (EBRT). The underlying molecular mechanisms remain unclear. This study investigated the differentially expressed genes/proteins and their association with fatigue intensification during EBRT. Fatigue scores measured by FACT-F and peripheral blood were collected prior to treatment (baseline D

Indexed as

Cancer-related fatigue (CRF)External beam radiation therapy (EBRT)Gene expressionLymphocyteProstate cancer

Identifiers

PMID30364895
PMCPMC6198670
OpenAlexW2888203341

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.