Evidence map›Paper›PMID 30364858›Full record

ArticleWorld journal of gastrointestinal oncology2018

Suguru Maruyama, Shinji Furuya, Kensuke Shiraishi, Hiroki Shimizu, Hidenori Akaike, Naohiro Hosomura, Yoshihiko Kawaguchi, Hidetake Amemiya, Hiromichi Kawaida, Makoto Sudo and 3 more

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastrointestinal oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
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  11. miR-181a-2-3p Stimulates Gastric Cancer ProgressionFrontiers in bioengineering and biotechnology · 2021
    Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Suguru MaruyamaFirst Department of Surgery, Faculty of Medicine University of Yamanashi, Yamanashi 409-3898, Japan.
Shinji FuruyaFirst Department of Surgery, Faculty of Medicine University of Yamanashi, Yamanashi 409-3898, Japan.
Kensuke ShiraishiFirst Department of Surgery, Faculty of Medicine University of Yamanashi, Yamanashi 409-3898, Japan.
Hiroki ShimizuFirst Department of Surgery, Faculty of Medicine University of Yamanashi, Yamanashi 409-3898, Japan.
Hidenori AkaikeFirst Department of Surgery, Faculty of Medicine University of Yamanashi, Yamanashi 409-3898, Japan.
Naohiro HosomuraFirst Department of Surgery, Faculty of Medicine University of Yamanashi, Yamanashi 409-3898, Japan.
Yoshihiko KawaguchiFirst Department of Surgery, Faculty of Medicine University of Yamanashi, Yamanashi 409-3898, Japan.
Hidetake AmemiyaFirst Department of Surgery, Faculty of Medicine University of Yamanashi, Yamanashi 409-3898, Japan.
Hiromichi KawaidaFirst Department of Surgery, Faculty of Medicine University of Yamanashi, Yamanashi 409-3898, Japan.
Makoto SudoFirst Department of Surgery, Faculty of Medicine University of Yamanashi, Yamanashi 409-3898, Japan.
Shingo InoueFirst Department of Surgery, Faculty of Medicine University of Yamanashi, Yamanashi 409-3898, Japan.
Hiroshi KonoFirst Department of Surgery, Faculty of Medicine University of Yamanashi, Yamanashi 409-3898, Japan.
Daisuke IchikawaFirst Department of Surgery, Faculty of Medicine University of Yamanashi, Yamanashi 409-3898, Japan. dichikawa@yamanashi.ac.jp.
University of Yamanashi · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the clinical utility of alpha-fetoprotein (AFP)-producing gastric cancer (AFPGC)-specific microRNA (miRNA) for monitoring and prognostic prediction of patients.

methodsWe performed a comprehensive miRNA array-based approach to compare miRNA expression levels between AFP-positive and AFP-negative cells in three patients with primary AFPGC. We next examined the expression levels of the selected miRNAs in five AFPGC and ten non-AFPGC tissue samples by quantitative reverse transcription-polymerase chain reaction to validate their utility. We also investigated the expression levels of the selected miRNA not only in tissue but also in plasma samples. Moreover, we investigated the relationship between plasma AFP levels and plasma selected miRNA expression levels, and also investigated the correlation of the selected miRNA expression levels and malignant potential.

resultsAmong the five miRNAs selected from the miRNA array results, the expression levels of

conclusion

Indexed as

Alpha-fetoproteinAlpha-fetoprotein producing gastric cancerGastric cancerMicroRNAmiR-122-5p

Identifiers

PMID30364858
PMCPMC6198302
OpenAlexW2897742364

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.