Evidence map›Paper›PMID 30364572›Full record

ArticleAlzheimer's & dementia (New York, N. Y.)2018

Hearing treatment for reducing cognitive decline: Design and methods of the Aging and Cognitive Health Evaluation in Elders randomized controlled trial.

Jennifer A Deal, Adele M Goman, Marilyn S Albert, Michelle L Arnold, Sheila Burgard, Theresa Chisolm, David Couper, Nancy W Glynn, Theresa Gmelin, Kathleen M Hayden and 8 more

2 registry-linked trialsOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia (New York, N. Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03243422 nacompletednot on this map

Aging and Cognitive Health Evaluation in Elders (ACHIEVE) Randomized Trial

TypeinterventionalSponsorJohns Hopkins Bloomberg School of Public HealthRan2018 to 2023Enrolled977ConditionsAging, Cognitive DeclineArmsSuccessful aging health education intervention, Hearing intervention
NCT04899037 recruitingnot on this mapstarted 2021, after this paper: background citation

Pilot Study to Evaluate the Long-term Chronic Care of Patients Who Could or do Utilize an Osseointegrated Device (OID)

TypeobservationalSponsorUniversity of South FloridaRan2021 to 2027Enrolled50ConditionsHearing Loss, Conductive, Hearing Loss, Mixed, Deafness, UnilateralArmsNo intervention
3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 107 citations in OpenAlex.

  1. Trial
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  10. Effect of Hearing Intervention Versus Health Education Control on Fatigue: A Secondary Analysis of the ACHIEVE Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Trial
  11. Hearing Impairment and Physical Activity and Physical Functioning in Older Adults: Baseline Results From the ACHIEVE Trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Trial
  12. Trial
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  14. Hearing Rehabilitative Treatment for Older Adults With Comorbid Hearing Loss and Depression: Effects on Depressive Symptoms and Executive Function.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2022
    Trial
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  16. Article
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  20. Impact of hearing aid usage on the quality of life of the older adult in KwaZulu-Natal.The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 11 institutions in 2 countries.

Jennifer A DealDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Adele M GomanDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Marilyn S AlbertDepartment of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Michelle L ArnoldCollege of Science and Mathematics, University of South Florida Sarasota - Manatee, Sarasota, FL, USA.
Sheila BurgardDepartment of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
Theresa ChisolmDepartment of Communication Sciences and Disorders, University of South Florida, Tampa, FL, USA.
David CouperDepartment of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
Nancy W GlynnDepartment of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA.
Theresa GmelinGraduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
Kathleen M HaydenDepartment of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Thomas MosleyThe MIND Center, University of Mississippi Medical Center, Jackson, MS, USA.
James S PankowDivision of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, MN, USA.
Nicholas ReedDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Victoria A SanchezDepartment of Otolaryngology-Head and Neck Surgery, University of South Florida, Tampa, FL, USA.
A Richey SharrettDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Sonia D ThomasRTI International, Research Triangle Park, NC, USA.
Josef CoreshDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Frank R LinDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Johns Hopkins Medicine · USJohns Hopkins University · USUniversity of North Carolina at Chapel Hill · USUniversity of Pittsburgh · USUniversity of South Florida · USCochlear (Australia) · AUMinnesota Department of Health · USRTI International · USUniversity of Mississippi Medical Center · USUniversity of South Florida Sarasota–Manatee · USWake Forest University · US

Funding

ARIC Neurocognitive Study (ARIC-NCS) Renewal 2023-2028U01HL096812 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI JOSEF CORESH, THOMAS H MOSLEY · 2010 to 2026
$65.7M
Aging, Cognition, and Hearing Evaluation in Elders (ACHIEVE) Randomized TrialR01AG055426 · NIA · JOHNS HOPKINS UNIVERSITY · PI CORESH, JOSEF, LIN, FRANK R · 2017 to 2021
$16.6M
Wake Forest Alzheimer's Disease Core CenterP30AG049638 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI WHITLOW, CHRISTOPHER T · 2016 to 2020
$12.2M
ARIC Neurocognitive Study (ARIC-NCS) Renewal 2 of 5U01HL096917 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI MOSLEY, THOMAS H · 2010 to 2018
$11.9M
ARIC Neurocognitive Study (ARIC-NCS) Renewal UNC 4 of 5U01HL096899 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COUPER, DAVID J · 2010 to 2018
$7.5M
ARIC Neurocognitive Study (ARIC-NCS)U01HL096902 · NHLBI · UNIVERSITY OF MINNESOTA · PI LUTSEY, PAMELA L. · 2010 to 2018
$7.4M
ARIC Neurocognitive Study (ARIC-NCS) Renewal 4 of 5U01HL096814 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUGHES, TIMOTHY M., WAGENKNECHT, LYNNE E · 2010 to 2018
$6.5M
The ARIC and Neurocognitive Longitudinal StudyR01HL070825 · NHLBI · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI MOSLEY, THOMAS H · 2002 to 2004
$5.1M
Role and Mechanism of Hearing Impairment in Cognitive Decline and DementiaK01AG054693 · NIA · JOHNS HOPKINS UNIVERSITY · PI DEAL, JENNIFER ANNE · 2017 to 2022
$773k
Planning a trial of hearing rehabilitative treatment to reduce cognitive declineR34AG046548 · NIA · JOHNS HOPKINS UNIVERSITY · PI CORESH, JOSEF, LIN, FRANK R · 2014 to 2015
$626k
Myocardial Fibrosis in Heart Failure in the ElderlyR03AG023291 · NIA · ST. FRANCIS HOSPITAL (ROSLYN, NY) · PI BARASCH, EDDY · 2004 to 2004
$55k
NHLBI NIH HHS HHSN268201100005CNHLBI NIH HHS HHSN268201100005GNHLBI NIH HHS HHSN268201100005INHLBI NIH HHS HHSN268201100006CNHLBI NIH HHS HHSN268201100007CNHLBI NIH HHS HHSN268201100007INHLBI NIH HHS HHSN268201100008CNHLBI NIH HHS HHSN268201100008INHLBI NIH HHS HHSN268201100009CNHLBI NIH HHS HHSN268201100009INHLBI NIH HHS HHSN268201100010CNHLBI NIH HHS HHSN268201100011CNHLBI NIH HHS HHSN268201100011INHLBI NIH HHS HHSN268201100012CNHLBI NIH HHS R01 HL070825NHLBI NIH HHS U01 HL096812NHLBI NIH HHS U01 HL096814NHLBI NIH HHS U01 HL096899NHLBI NIH HHS U01 HL096902NHLBI NIH HHS U01 HL096917NIA NIH HHS K01 AG054693NIA NIH HHS P30 AG049638NIA NIH HHS R01 AG055426NIA NIH HHS R03 AG023291NIA NIH HHS R34 AG046548
6 · The paper itself

Abstract

introductionHearing impairment is highly prevalent and independently associated with cognitive decline. The Aging and Cognitive Health Evaluation in Elders study is a multicenter randomized controlled trial to determine efficacy of hearing treatment in reducing cognitive decline in older adults. Clinicaltrials.gov Identifier: NCT03243422.

methodsEight hundred fifty participants without dementia aged 70 to 84 years with mild-to-moderate hearing impairment recruited from four United States field sites and randomized 1:1 to a best-practices hearing intervention or health education control. Primary study outcome is 3-year change in global cognitive function. Secondary outcomes include domain-specific cognitive decline, incident dementia, brain structural changes on magnetic resonance imaging, health-related quality of life, physical and social function, and physical activity.

resultsTrial enrollment began January 4, 2018 and is ongoing. DISCUSSION: When completed in 2022, Aging and Cognitive Health Evaluation in Elders study should provide definitive evidence of the effect of hearing treatment versus education control on cognitive decline in community-dwelling older adults with mild-to-moderate hearing impairment.

Indexed as

Clinical trialsCognitionDementiaEpidemiologyHearingLongitudinal studyMemoryPresbycusis

Identifiers

PMID30364572
PMCPMC6197326
OpenAlexW2894917382

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.