Evidence map›Paper›PMID 30364263›Full record

ArticleCell & bioscience2018

A role of Pumilio 1 in mammalian oocyte maturation and maternal phase of embryogenesis.

Winifred Mak, Jing Xia, Ee-Chun Cheng, Katie Lowther, Haifan Lin

Open access · goldAbstract read
In one paragraph

Article in Cell & bioscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Winifred Mak3Division of Reproductive Endocrinology and Infertility, Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06519 USA.
Jing Xia1Yale Stem Cell Center, Yale University School of Medicine, 10 Amistad Street, New Haven, CT 06519 USA.
Ee-Chun Cheng1Yale Stem Cell Center, Yale University School of Medicine, 10 Amistad Street, New Haven, CT 06519 USA.
Katie Lowther6University of Connecticut Health Center, Farmington, CT 06030 USA.
Haifan Lin1Yale Stem Cell Center, Yale University School of Medicine, 10 Amistad Street, New Haven, CT 06519 USA.ORCID 0000-0002-5374-9491
Yale Cancer Center · USShanghaiTech University · CNUConn Health · USYale University · US

Funding

The Yale WRHR Career Development CenterK12HD047018 · NICHD · YALE UNIVERSITY · PI Hugh Smith Taylor · 2004 to 2026
$7.8M
Translational Regulation of Embryonic Stem Cell Self-Renewal by Pumlio ProteinsR01GM121386 · NIGMS · YALE UNIVERSITY · PI QI, HONGYING · 2017 to 2020
$1.5M
NICHD NIH HHS K12 HD047018NIGMS NIH HHS R01 GM121386
6 · The paper itself

Abstract

backgroundRNA binding proteins play a pivotal role during the oocyte-to-embryo transition and maternal phase of embryogenesis in invertebrates, but their function in these processes in mammalian systems remain largely understudied.

resultsHere we report that a member of the Pumilio/FBF family of RNA binding proteins in mice, Pumilio 1 (

conclusionsThese findings indicate that PUM1 is essential in the process of cytoplasmic maturation and developmental competence of the oocyte. These results reveal an important function of maternal PUM1 as a post-transcriptional regulator during mammalian embryogenesis.

Indexed as

Oocyte maturationPost-transcriptional regulationPreimplantation embryo

Identifiers

PMID30364263
PMCPMC6194604
OpenAlexW2896735725

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.