ArticleCase reports in surgery2018
Gigantic GIST: A Case of the Largest Gastrointestinal Stromal Tumor Found to Date.
Article in Case reports in surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Article
- Article
- Giant gastric GIST with fast-growing mass after intra-tumoral bleeding.Journal of surgical case reports · 2023Article
- Rare serosal cystic gastric gastrointestinal stromal tumor with extensive intestinal metaplasia in an adherent gastric mucosa; a case report in a 65-year-old male.Journal of surgical case reports · 2023Article
- Do you get the GIST? Successful resection of a giant 3.5 kg gastrointestinal stromal tumour.ANZ journal of surgery · 2022Article
- Get the GIST: A Case Study of Detection and Treatment of Gastrointestinal Stromal Tumors.Cureus · 2020Article
- Postsurgical gastroparesis syndrome (PGS) following sleeve resection of a giant (6.1 kg) gastric gastrointestinal stromal tumour (GIST).BMJ case reports · 2020Article
- Large incidental gastrointestinal stromal tumors in a patient presenting with acutely symptomatic nephrolithiasis: A case report.Radiology case reports · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
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Abstract
Gastrointestinal stromal tumors are uncommon when compared to all gastrointestinal neoplasms but are the most common mesenchymal tumors of the gastrointestinal tract. The largest gastrointestinal stromal tumor ever recorded in literature weighed approximately 6.1 kg and measured 39 cm × 27 cm × 14 cm. About two-thirds of GISTs are malignant. The tumor size, mitotic rate, cellularity, and nuclear pleomorphism are the most important parameters when considering prognosis and recurrence. The definitive treatment for these tumors is resection. In the year 2000, the first patient was treated with the tyrosine kinase inhibitor imatinib and since then, gastrointestinal stromal tumors with high-risk features have been treated successfully with tyrosine kinase inhibitors. We present the largest gastrointestinal stromal tumor recorded in medical literature measuring 42.0 cm × 31.0 cm × 23.0 cm in maximum dimensions and weighing in at approximately 18.5 kg in a 65-year-old African-American male who presented with increased abdominal distention. The mass was successfully excised, and the patient was treated with imatinib without local or distant recurrence 1.5 years postoperatively.
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Registered trials
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