Evidence map›Paper›PMID 30363942›Full record

ArticleMovement disorders clinical practice2015

Abnormalities of Masseteric Inhibitory Reflex in Hereditary Geniospasm: Evidence for a Brainstem Myoclonus.

Antonella Macerollo, Tabish A Saifee, Panagiotis Kassavetis, Giovanna Pilurzi, Susanne A Schneider, Mark J Edwards, Kailash P Bhatia

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Movement disorders clinical practice, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Effective Treatment of Geniospasm: Case Series and Review of the Literature.Tremor and other hyperkinetic movements (New York, N.Y.) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Antonella MacerolloSobell Department of Motor Neuroscience and Movement Disorders UCL Institute of Neurology London United Kingdom.
Tabish A SaifeeSobell Department of Motor Neuroscience and Movement Disorders UCL Institute of Neurology London United Kingdom.
Panagiotis KassavetisSobell Department of Motor Neuroscience and Movement Disorders UCL Institute of Neurology London United Kingdom.
Giovanna PilurziSobell Department of Motor Neuroscience and Movement Disorders UCL Institute of Neurology London United Kingdom.
Susanne A SchneiderDepartment of Neurology University Kiel Kiel Germany.
Mark J EdwardsSobell Department of Motor Neuroscience and Movement Disorders UCL Institute of Neurology London United Kingdom.
Kailash P BhatiaSobell Department of Motor Neuroscience and Movement Disorders UCL Institute of Neurology London United Kingdom.
Sobell House · GBKiel University · DEUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied two unrelated families with several members suffering from geniospasm. Here, we aim to clarify the pathophysiology underlying the hereditary geniospasm through testing of brainstem excitability by the recovery cycles of the blink reflex (BR) and the masseteric inhibitory reflex (MIR). The R2 component of the BR and the SP2 component of the MIR and their recovery cycle were analyzed in 3 patients and 8 healthy, age-matched subjects as the control group. Patients with geniospasm exhibited a different excitability of the BR, compared to the control, group, as shown by the larger R2 component area of BR in controls than patients. Notably, the mean recovery index was 0.61 ± 0.19 in geniospasm patients and 0.40 ± 0.15 in controls (

Indexed as

blink reflex recovery cyclebrainstem excitabilitymasseteric inhibitory reflex

Identifiers

PMID30363942
PMCPMC6183308
OpenAlexW2101081315

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.