Evidence map›Paper›PMID 30363903›Full record

ArticleMovement disorders clinical practice2015

Safe Administration of Botulinum Toxin Type A Injections During Pregnancy: A Report of Two Cases.

Henriette Krug, Patricia Krause, Andreas Kupsch, Andrea A Kühn

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Movement disorders clinical practice, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Botulinum Toxin Treatment in Pregnant Laryngeal Dystonia Patients: Case Series and Survey of Current Practice of Canadian Laryngologists.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Henriette KrugDepartment of Neurology Charité-University Medicine Berlin Berlin Germany.
Patricia KrauseDepartment of Neurology Charité-University Medicine Berlin Berlin Germany.
Andreas KupschDepartment of Neurology and Functional Neurosurgery Otto von Guericke University Magdeburg Germany.
Andrea A KühnDepartment of Neurology Charité-University Medicine Berlin Berlin Germany.
Charité - Universitätsmedizin Berlin · DEOtto-von-Guericke University Magdeburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Local injections of botulinum toxin type A (BoNT/A) are safe and efficacious to treat focal and segmental dystonia. However, there are no adequate studies in humans regarding the safety of BoNT/A during pregnancy. Despite the fact that 25 case reports have been published on patients who received BoNT/A injections during a total of 31 pregnancies, in only 3 patients were the injections continued beyond the first trimester. We report on 2 females with cervical and segmental dystonia who received BoNT/A injections during pregnancy beyond the first trimester and gave birth to 2 healthy children.

Indexed as

botulinum toxindystoniamovement disordersobstetricspregnancy

Identifiers

PMID30363903
PMCPMC6183313
OpenAlexW1554328971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.