Evidence map›Paper›PMID 30363828›Full record

ArticleMovement disorders clinical practice2014

Clinico-Pathological Correlation in Progressive Ataxia and Palatal Tremor: A Novel Tauopathy.

Zoltan Mari, Andrew J M Halls, Alexander Vortmeyer, Victoria Zhukareva, Kunihiro Uryu, Virginia M-Y Lee, Mark Hallett

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Movement disorders clinical practice, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Classification of diseases with accumulation of Tau protein.Neuropathology and applied neurobiology · 2022
    Article
  4. Clinical and Imaging Profile of Patients with Palatal Tremor.Movement disorders clinical practice · 2021
    Article
  5. Review
  6. Some New and Unexpected Tauopathies in Movement Disorders.Movement disorders clinical practice · 2020
    Article
  7. A Treatable Rare Cause of Progressive Ataxia and Palatal Tremor.Tremor and other hyperkinetic movements (New York, N.Y.) · 2018
    Article
  8. Review
  9. Palatal Tremor inMovement disorders clinical practice · 2015
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Zoltan MariHuman Motor Control Section Medical Neurology Branch National Institute of Neurological Disorders and Stroke National Institutes of Health Bethesda Maryland USA.
Andrew J M HallsDepartment of Neurology Johns Hopkins University School of Medicine Baltimore Maryland USA.
Alexander VortmeyerSurgical Neurology Branch National Institute of Neurological Disorders and Stroke National Institutes of Health Bethesda Maryland USA.
Victoria ZhukarevaCenter for Neurodegenerative Disease Research Department of Pathology and Laboratory Medicine University of Pennsylvania School of Medicine Philadelphia Pennsylvania USA.
Kunihiro UryuCenter for Neurodegenerative Disease Research Department of Pathology and Laboratory Medicine University of Pennsylvania School of Medicine Philadelphia Pennsylvania USA.
Virginia M-Y LeeCenter for Neurodegenerative Disease Research Department of Pathology and Laboratory Medicine University of Pennsylvania School of Medicine Philadelphia Pennsylvania USA.
Mark HallettHuman Motor Control Section Medical Neurology Branch National Institute of Neurological Disorders and Stroke National Institutes of Health Bethesda Maryland USA.
University of Pennsylvania · USJohns Hopkins Medicine · USJohns Hopkins University · USNational Institute of Neurological Disorders and Stroke · USNational Institutes of Health · USRockefeller University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Palatal tremor (PT) is an uncommon movement disorder that has been subdivided into essential and symptomatic forms. A distinct subgroup of the symptomatic form presents with progressive ataxia and PT. The histopathology of progressive ataxia and PT has not been previously determined. This study consisted of a clinical review, histopathology, and electron microscopy of the brain of a man with progressive ataxia and PT. The inferior olivary hypertrophy was symmetrical and homogenous, and no focal pathologic lesions could be identified in the brainstem. Insoluble tau deposits were found in neurons, exclusively infratentorially. We present the clinical and pathological evaluation of a case of progressive ataxia and PT that provide evidence for a unique form of 4R tauopathy.

Indexed as

ataxianeurodegenerative disordersneuropathologytremor

Identifiers

PMID30363828
PMCPMC6183254
OpenAlexW2010203095

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.