Evidence map›Paper›PMID 30363761›Full record

ArticleCase reports in hematology2018

Splenic B-Cell Lymphomas with Diffuse Cyclin D1 Protein Expression and Increased Prolymphocytic Cells: A Previously Unrecognized Diagnostic Pitfall.

Khaled Algashaamy, Yaohong Tan, Nicolas Mackrides, Alvaro Alencar, Jing-Hong Peng, Joseph Rosenblatt, Juan P Alderuccio, Izidore S Lossos, Francisco Vega, Jennifer Chapman

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in hematology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Khaled AlgashaamyDepartment of Pathology, Division of Hematopathology, University of Miami, Sylvester Comprehensive Cancer Center and Jackson Memorial Hospital, Miami, Florida, USA.
Yaohong TanDepartment of Pathology, Division of Hematopathology, University of Miami, Sylvester Comprehensive Cancer Center and Jackson Memorial Hospital, Miami, Florida, USA.
Nicolas MackridesDepartment of Pathology, Division of Hematopathology, University of Miami, Sylvester Comprehensive Cancer Center and Jackson Memorial Hospital, Miami, Florida, USA.
Alvaro AlencarDepartment of Medicine, Division of Hematology-Oncology, University of Miami, Sylvester Comprehensive Cancer Center and Jackson Memorial Hospital, Miami, Florida, USA.
Jing-Hong PengDepartment of Pathology, Division of Hematopathology, University of Miami, Sylvester Comprehensive Cancer Center and Jackson Memorial Hospital, Miami, Florida, USA.
Joseph RosenblattDepartment of Medicine, Division of Hematology-Oncology, University of Miami, Sylvester Comprehensive Cancer Center and Jackson Memorial Hospital, Miami, Florida, USA.
Juan P AlderuccioDepartment of Medicine, Division of Hematology-Oncology, University of Miami, Sylvester Comprehensive Cancer Center and Jackson Memorial Hospital, Miami, Florida, USA.
Izidore S LossosDepartment of Medicine, Division of Hematology-Oncology, University of Miami, Sylvester Comprehensive Cancer Center and Jackson Memorial Hospital, Miami, Florida, USA.
Francisco VegaDepartment of Pathology, Division of Hematopathology, University of Miami, Sylvester Comprehensive Cancer Center and Jackson Memorial Hospital, Miami, Florida, USA.ORCID 0000-0001-5956-452X
Jennifer ChapmanDepartment of Pathology, Division of Hematopathology, University of Miami, Sylvester Comprehensive Cancer Center and Jackson Memorial Hospital, Miami, Florida, USA.ORCID 0000-0002-6214-4152
University of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prolymphocytic transformation is a concept usually applied in the context of chronic lymphocytic leukemia/small lymphocytic lymphoma to describe the presence of a high percentage of prolymphocytes in peripheral blood (usually more than 55%). Prolymphocytic transformation has also been reported in mantle cell lymphoma (MCL) but only rarely in splenic marginal zone lymphoma (SMZL). We present two splenic B-cell lymphomas presenting in the leukemic phase and with increased prolymphocytes, both classified as SMZL with prolymphocytic transformation. One case clinically simulated B-prolymphocytic leukemia (B-PLL). Both lymphomas were very unusual because the tumor cells diffusely and strongly expressed cyclin D1 despite lacking the t(11; 14)(q13; q32) as detected by several approaches including next-generation sequencing, fluorescence

Identifiers

PMID30363761
PMCPMC6180998
OpenAlexW2892897921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.