Evidence map›Paper›PMID 30363747›Full record

ArticleCanadian journal of gastroenterology & hepatology2018

Management Strategies and Outcomes for Hyponatremia in Cirrhosis in the Hyponatremia Registry.

Samuel H Sigal, Alpesh Amin, Joseph A Chiodo, Arun Sanyal

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Canadian journal of gastroenterology & hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Evidence-based hyponatremia management in liver disease.Clinical and molecular hepatology · 2023
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Hyponatremia in Cirrhosis.Clinics in liver disease · 2022
    Review
  11. Hyponatremia in Infectious Diseases-A Literature Review.International journal of environmental research and public health · 2020
    Review
  12. Evidence for Effective Multiple KFrontiers in pharmacology · 2019
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Samuel H SigalDepartment of Medicine, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, New York 10467, USA.ORCID 0000-0003-1092-8083
Alpesh AminDepartment of Medicine, University of California, Irvine, California 92868, USA.
Joseph A ChiodoAgile Therapeutics, Inc., Princeton, New Jersey 08540, USA.
Arun SanyalVirginia Commonwealth University Medical Center, Richmond, Virginia 23298, USA.
Agile Therapeutics (United States) · USAlbert Einstein College of Medicine · USUniversity of California, Irvine · USVirginia Commonwealth University Medical Center · US

Funding

Research Supplement to Promote Diversity in Health Related ResearchUL1TR002649 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2018 to 2022
$19.1M
6 · The paper itself

Abstract

Aim: Treatment practices and effectiveness in cirrhotic patients with hyponatremia (HN) in the HN Registry were assessed. Methods: Characteristics, treatments, and outcomes were compared between patients with HN at admission and during hospitalization. For HN at admission, serum sodium concentration [Na] response was analyzed until correction to > 130 mmol/L, switch to secondary therapy, or discharge or death with sodium ≤ 130 mmol/L. Results: Patients with HN at admission had a lower [Na] and shorter length of stay (LOS) than those who developed HN ( Conclusions: Treatment approaches for HN were variable and frequently ineffective. Success was greatest with HS and Tol. Relapse of HN is associated with increased LOS.

Indexed as

AgedAntidiuretic AgentsFemaleFluid TherapyHospitalizationHumansHyponatremiaIsotonic SolutionsLiver CirrhosisMaleMiddle AgedRecurrenceRegistriesSodiumTolvaptanTreatment OutcomeAntidiuretic AgentsIsotonic SolutionsSodiumTolvaptan

Identifiers

PMID30363747
PMCPMC6180997
OpenAlexW2893490888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.