Evidence map›Paper›PMID 30363643›Full record

ReviewTranslational gastroenterology and hepatology2018

Role of associating liver partition and portal vein ligation in staged hepatectomy (ALPPS)-strategy for colorectal liver metastases.

Arezou Abbasi, Amir A Rahnemai-Azar, Katiuscha Merath, Sharon M Weber, Daniel E Abbott, Mary Dillhoff, Jordan Cloyd, Timothy M Pawlik

Open access · hybridAbstract readReview
In one paragraph

Review in Translational gastroenterology and hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Postoperative Liver Failure: Definitions, Risk factors, Prediction Models and Prevention Strategies.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
    Review
  3. Review
  4. Short-Term Outcomes of Patients Undergoing Portal Vein Embolization: an ACS-NSQIP Procedure-Targeted Hepatectomy Analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020
    Article
  5. Article
  6. New trends and perspectives in hepatobiliary surgery: preface.Translational gastroenterology and hepatology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Arezou AbbasiDepartment of Surgery, Division of Surg Oncol, University of Washington, Seattle, WA, USA.
Amir A Rahnemai-AzarDepartment of Surgery, Division of Surg Oncol, University of Wisconsin, Madison, WI, USA.
Katiuscha MerathDepartment of Surgery, Division of Surg Oncol, Ohio State University, Columbus, OH, USA.
Sharon M WeberDepartment of Surgery, Division of Surg Oncol, University of Wisconsin, Madison, WI, USA.
Daniel E AbbottDepartment of Surgery, Division of Surg Oncol, University of Wisconsin, Madison, WI, USA.
Mary DillhoffDepartment of Surgery, Division of Surg Oncol, Ohio State University, Columbus, OH, USA.
Jordan CloydDepartment of Surgery, Division of Surg Oncol, Ohio State University, Columbus, OH, USA.
Timothy M PawlikDepartment of Surgery, Division of Surg Oncol, Ohio State University, Columbus, OH, USA.
The Ohio State University · USUniversity of Wisconsin–Madison · USUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal carcinoma (CRC) is the third leading cause of cancer-related death in the United States. The liver is the most frequent site of metastasis and a key determinant of survival in patients with isolated colorectal liver metastasis (CRLM). Surgical resection remains the only hope for prolonged survival in patients with CRLM. However, most patients are deemed to be unresectable at presentation due to a small future liver remnant (FLR) and fear of post-hepatectomy liver failure. Procedures such as portal vein ligation or embolization (PVL/PVE) followed by hepatectomy have been established as standard methods to increase FLR volume, but have limitations dependent upon extent of disease and patient's ability to grow the liver remnant. Recently, associating liver partition and portal vein ligation in staged hepatectomy (ALPPS) has been introduced as a technique to induce liver hypertrophy over a shorter time period. Being a complex two-stage surgical procedure, initial reports of higher ALPPS-associated complications and mortality limited its worldwide adoption by hepatobiliary surgeons. However, recent studies have showed ALPPS superiority over conventional procedures in terms of feasibility and inducing liver hypertrophy, with comparable morbidity and mortality. We herein review the role of ALPPS in management of patients with CRLM.

Indexed as

Associating liver partition and portal vein ligation in staged hepatectomy (ALPPS)colorectalliveroutcomes

Identifiers

PMID30363643
PMCPMC6182023
OpenAlexW2890024015

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.