ArticleMovement disorders clinical practice
Malignant Subthalamic Nucleus-Deep Brain Stimulation Withdrawal Syndrome in Parkinson's Disease.
Article in Movement disorders clinical practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 41 citations in OpenAlex.
- Retrospective Multicenter Analysis of Withdrawal Syndrome in Parkinson's Disease Patients After Cessation of Deep Brain Stimulation.Diagnostics (Basel, Switzerland) · 2026Article
- Parkinsonism-Hyperpyrexia Syndrome Following Deep Brain Stimulation Battery Depletion during the COVID-19 Pandemic: A Case Series and Review of the Literature.Movement disorders clinical practice · 2026Review
- New insights from a Malaysian real-world deep brain stimulation cohort.Journal of Parkinson's disease · 2025Article
- A frugal suggestion from a functional neurosurgeon to the german guidelines on treatment of the "DBS withdrawal syndrome".Journal of neurology · 2024Article
- Akinetic crisis and withdrawal syndromes: guideline "Parkinson's disease" of the German Society of Neurology.Journal of neurology · 2024Review
- Anthropology of Deep Brain Stimulation; the 30th Anniversary of STN DBS in 2023.Movement disorders clinical practice · 2023Review
- Deep brain stimulation for Parkinson's disease.Journal of internal medicine · 2022Review
- Article
- Pallidotomy: A "Phoenix the Bird" of Surgery for Parkinson's Disease?Movement disorders clinical practice · 2022Article
- Treatment of focal hand dystonia: current status.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Review
- Management of Parkinson's Disease in the COVID-19 Pandemic and Future Perspectives in the Era of Vaccination.Journal of movement disorders · 2021Article
- Management of Advanced Therapies in Parkinson's Disease Patients in Times of Humanitarian Crisis: The COVID-19 Experience.Movement disorders clinical practice · 2020Review
- Challenges in PD Patient Management After DBS: A Pragmatic Review.Movement disorders clinical practiceReview
- Spectrum of Movement Disorder Emergencies in a Tertiary Care Center in India: A Prospective Observational Study.Annals of Indian Academy of NeurologyArticle
- Movement Disorder Emergencies: When "Too Much" or "Too Little" Movement Needs Urgent Attention!!Annals of Indian Academy of NeurologyArticle
- Deep Brain Stimulation Withdrawal Syndrome in Parkinson's Disease: Clinical Features and Outcomes of Two New Cases.Case reports in neurologyArticle
- A Study of Battery Replacement Characteristics of Patients With Parkinson's Disease and Factors Influencing Battery Drain.Annals of Indian Academy of NeurologyArticle
- Once STN DBS, Always STN DBS?-Clinical, Ethical, and Financial Reflections on Deep Brain Stimulation for Parkinson's Disease.Movement disorders clinical practiceArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Abrupt cessation of STN-DBS is an under-recognized cause of life-threatening akinetic crisis in Parkinson's disease (PD) and can present as a movement disorder emergency. We report on 2 patients who survived severe and prolonged akinetic crisis after abrupt cessation of STN stimulation for PD (malignant STN-DBS withdrawal syndrome). We discuss the clinical similarities and possible differences in pathophysiology from the akinetic crisis in medically-treated PD. Although early implantable pulse generator (IPG) replacement is the definitive treatment, medical and economic considerations may preclude early surgery and strategies for medical management assume importance. We reflect upon the socioeconomic concerns surrounding DBS in countries lacking health care coverage and the need for user-independent monitors and indicators of low IPG battery status.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.