ReviewMovement disorders clinical practice2015
Nonmotor Symptoms in Dopa-Responsive Dystonia.
Review in Movement disorders clinical practice, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Therapeutic effects of striatal dopaminergic modulation on idiopathic dystonia and OCD in humans: insights from the striosome hypothesis.Frontiers in human neuroscience · 2025Article
- Segawa Syndrome, a Dramatic Response to Dopamine.Case reports in neurological medicine · 2024Article
- Myoclonus-Dystonic Presentation of Childhood Onset DYT-GCH1: A Report From India.Journal of movement disorders · 2023Article
- Neuropsychiatric and sleep study in autosomal dominant dopa-responsive dystonia.Molecular genetics and metabolism reports · 2022Article
- Recognizing Atypical Dopa-Responsive Dystonia and Its Mimics.Neurology. Clinical practice · 2021Review
- Personalized Medicine to Improve Treatment of Dopa-Responsive Dystonia-A Focus on Tyrosine Hydroxylase Deficiency.Journal of personalized medicine · 2021Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDopa-responsive dystonia (DRD) is a rare inherited dystonia, caused by an autosomal dominantly inherited defect in the gene
methodsHere by searching the Medline database for publications between 1971 to March 2015, we render an in-depth analysis of all published data on non-motor symptoms in DRD.
resultsDepression and subtle sleep quality impairment have been reported among the different cohorts, while current data do not support any alterations of the cardiologic and autonomic systems. However, there is debate about the occurrence of sleep-related movement disorders and cognitive function. Non-motor symptoms are instead frequently reported among the clinical spectrum of other neurotransmitter disorders which may sometimes mimic DRD phenotype, ie, DRD plus diseases.
conclusionsFurther studies in larger and treatment-naïve cohorts are needed to better elucidate the extend of non-motor symptoms in DRD and also to consider treatment for these.
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Registered trials
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