ArticleMovement disorders clinical practice
Quantitative Measurement of Akinesia in Parkinson's Disease.
Article in Movement disorders clinical practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Digital Devices for Assessing Motor Functions in Mobility-Impaired and Healthy Populations: Systematic Literature Review.Journal of medical Internet research · 2022Pooled it
- Reliability and validity of the Roche PD Mobile Application for remote monitoring of early Parkinson's disease.Scientific reports · 2022Trial
- Exploring cerebral small vessel disease signatures in familial Parkinson's disease.Scientific reports · 2026Article
- Parkinson's Disease: Exploring Different Animal Model Systems.International journal of molecular sciences · 2023Review
- Parkinsonian Hand or Clinician's Eye? Finger Tap Bradykinesia Interrater Reliability for 21 Movement Disorder Experts.Journal of Parkinson's disease · 2023Article
- Exploring the Complex Phenotypes of Impaired Finger Dexterity in Mild-to-moderate Stage Parkinson's Disease: A Time-Series Analysis.Journal of Parkinson's disease · 2023Article
- Deep Clinical Phenotyping of Parkinson's Disease: Towards a New Era of Research and Clinical Care.Phenomics (Cham, Switzerland) · 2022Review
- Digital Technology in Movement Disorders: Updates, Applications, and Challenges.Current neurology and neuroscience reports · 2021Review
- Video-based quantification of human movement frequency using pose estimation: A pilot study.PloS one · 2021Article
- Touchscreen-based finger tapping: Repeatability and configuration effects on tapping performance.PloS one · 2021Article
- Development of digital biomarkers for resting tremor and bradykinesia using a wrist-worn wearable device.NPJ digital medicine · 2020Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is great interest in developing simple, user-friendly, and inexpensive tools for the quantification and elucidation of motor deficits in patients with Parkinson's disease (PD). These systems could help to monitor the clinical status of patients with PD, to develop better treatments, and to identify individuals who have subtle motor signs that might pass unnoticed in the conventional neurological examination.
methodsMememtum, a smartphone application that allows for the quantification of several parameters of movement, such as regularity, rhythm, and changes in the number of taps while taping with a single finger and with alternating fingers, was developed and then tested in a pilot study in Madrid and in an extensive study in Quito, Ecuador.
resultsAlmost all patients could successfully perform single-finger tapping, but approximately 10% of patients with severe parkinsonism had problems taping with alternating fingers. The results revealed changes in the regularity of the pressure applied while tapping and a reduction in the number of taps on the device screen when alternating tapping among patients who had idiopathic PD and vascular parkinsonism compared with controls and individuals who had prediagnostic motor abnormalities of PD.
conclusionApplications available in smartphones could be used for investigation and treatment of patients with PD, but much research is needed to optimize the ideal parameters to be investigated and the potential usefulness of this technique for patients with PD in different stages of the disease.
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