ArticleMovement disorders clinical practice
Olfactory Impairment Predicts Underlying Dopaminergic Deficit in Presumed Drug-Induced Parkinsonism.
Article in Movement disorders clinical practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Comparative Olfactory Profiles in Parkinson's Disease and Drug-Induced Parkinsonism.Journal of movement disorders · 2024Article
- Neuroimaging Techniques in Differentiating Parkinson's Disease from Drug-Induced Parkinsonism: A Comprehensive Review.Clinics and practice · 2023Review
- Gait abnormalities and non-motor symptoms predict abnormal dopaminergic imaging in presumed drug-induced Parkinsonism.NPJ Parkinson's disease · 2022Article
- Updated Perspectives on the Management of Drug-Induced Parkinsonism (DIP): Insights from the Clinic.Therapeutics and clinical risk management · 2022Review
- Olfactory Testing in Parkinson Disease and REM Behavior Disorder: A Machine Learning Approach.Neurology · 2021Article
- Olfactory Deficits in the Freezing of Gait Phenotype of Parkinson's Disease.Frontiers in neurology · 2021Article
- Early and Accurate Identification of Parkinson Disease Among US Veterans.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2019Article
- Olfactory Dysfunction as an Early Biomarker in Parkinson's Disease.Neuroscience bulletin · 2017Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Drug-induced parkinsonism (DIP) is common, and the motor symptoms can be indistinguishable from Parkinson's disease (PD). When symptoms persist after drug withdrawal, this may represent "unmasking" of underlying PD. We previously reported that hyposmia, a common nonmotor feature of PD, was associated with persistent DIP. Here, we report on a series of 33 consecutive patients who underwent dopamine transporter imaging to evaluate DIP. We examined the clinical correlates of underlying dopaminergic denervation by comparing subjects with normal and abnormal scans. Imaging was abnormal in 7 of 33 (21%) cases. Motor features were similar in patients with normal and abnormal scans. Olfactory testing was available for 30 subjects and was concordant with imaging in 27 of 30 (odds ratio = 63; 95% confidence interval: 4.8-820;
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.