Evidence map›Paper›PMID 30363012›Full record

ReviewMenopause (New York, N.Y.)2019

A pooled analysis of three studies of nonpharmacological interventions for menopausal hot flashes.

Nancy E Avis, Beverly J Levine, Suzanne Danhauer, Remy R Coeytaux

Abstract readReview
In one paragraph

Review in Menopause (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nancy E AvisDepartment of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, NC.
Beverly J LevineDepartment of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, NC.
Suzanne DanhauerDepartment of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, NC.
Remy R CoeytauxDepartment of Family and Community Medicine, Wake Forest School of Medicine, Winston-Salem, NC.
Wake Forest University · US

Funding

Non-specific Effects of Acupuncture in the Treatment of Hot FlashesR01AT005854 · NCCIH · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI AVIS, NANCY E · 2010 to 2014
$2.0M
Effectiveness of Integral Yoga on Objective and Subjective Menopausal Hot FlashesR21AT004234 · NCCIH · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI AVIS, NANCY E · 2009 to 2011
$883k
Acupuncture Treatment for Menopausal Hot FlashesR21CA104427 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI AVIS, NANCY E · 2004 to 2005
$346k
NCCIH NIH HHS R01 AT005854NCCIH NIH HHS R21 AT004234NCI NIH HHS R21 CA104427
6 · The paper itself

Abstract

objectiveThe aim of the study was to conduct a pooled analysis of three published trials of nonpharmacological interventions for menopausal hot flashes to compare the effectiveness of interventions.

methodsData from three randomized controlled trials of interventions for hot flashes (two acupuncture trials, one yoga trial) were pooled. All three studies recruited perimenopausal or postmenopausal women experiencing ≥4 hot flashes/d on average. The primary outcome for all three studies was frequency of hot flashes as measured by the Daily Diary of Hot Flashes. Study 1 participants were randomly assigned to 8 weeks of acupuncture treatments (active intervention), sham acupuncture (attention control), or usual care. Study 2 participants were randomly assigned to 10 weeks of yoga classes, health and wellness education classes (attention control), or waitlist control. Study 3 randomly assigned participants to 6 months of acupuncture or waitlist control. To standardize the time frame for these analyses, only the first 8 weeks of intervention from all three studies were used.

resultsThe three active interventions and the two attention control groups had statistically similar trends in the percentage reduction of hot flashes over 8 weeks, ranging from 35% to 40%. These five groups did not differ significantly from each other, but all showed significantly greater reduction in hot flash frequency compared with the three usual care/waitlist groups.

conclusionAcupuncture, yoga, and health and wellness education classes all demonstrated statistically similar effectiveness in reduction of hot flash frequency compared with controls.

Indexed as

Acupuncture TherapyMenopauseYogaFemaleHot FlashesHumansRandomized Controlled Trials as Topic

Identifiers

PMID30363012
PMCPMC6435413
OpenAlexW2898277574

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.