Evidence map›Paper›PMID 30362964›Full record

ArticleAging2018

Radiogenomics of lower-grade gliomas: a radiomic signature as a biological surrogate for survival prediction.

Zenghui Qian, Yiming Li, Zhiyan Sun, Xing Fan, Kaibin Xu, Kai Wang, Shaowu Li, Zhong Zhang, Tao Jiang, Xing Liu and 1 more

Abstract readMulticenter Study
In one paragraph

Article in Aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
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  6. Article
  7. Article
  8. Radiomics in glioma: emerging trends and challenges.Annals of clinical and translational neurology · 2025
    Review
  9. Review
  10. Artificial intelligence-based MRI radiomics and radiogenomics in glioma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zenghui Qian *Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Yiming Li *Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Zhiyan SunBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Xing FanBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Kaibin XuChinese Academy of Sciences, Institute of Automation, Beijing, China.
Kai WangDepartment of Nuclear Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Shaowu LiBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Zhong ZhangDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Tao JiangBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Xing LiuBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Yinyan WangDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to identify a radiomic signature to be used as a noninvasive biomarker of prognosis in patients with lower-grade gliomas (LGGs) and to reveal underlying biological processes through comprehensive radiogenomic investigation.

methodsWe extracted 55 radiomic features from T2-weighted images of 233 patients with LGGs (training cohort:

resultsThe six-feature radiomic signature stratified patients in the training cohort into low- or high-risk groups for overall survival (

conclusionsOur results suggest a great potential for the use of radiomic signature as a biological surrogate in providing prognostic information for patients with LGGs.

Indexed as

TranscriptomeAdultBiomarkers, TumorBrain NeoplasmsClinical Decision-MakingDecision Support TechniquesFemaleGene Expression ProfilingGliomaHumansMagnetic Resonance ImagingMaleMiddle AgedNeoplasm GradingNomogramsPrecision MedicineBiomarkers, Tumorbiomarkersgeneticsgliomasmagnetic resonance imagingprognosis

Identifiers

PMID30362964
PMCPMC6224242

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.