Evidence map›Paper›PMID 30362926›Full record

ArticleMonoclonal antibodies in immunodiagnosis and immunotherapy2018

Establishment of P38Bf, a Core-Fucose-Deficient Mouse-Canine Chimeric Antibody Against Dog Podoplanin.

Yukinari Kato, Takuya Mizuno, Shinji Yamada, Takuro Nakamura, Shunsuke Itai, Miyuki Yanaka, Masato Sano, Mika K Kaneko

Open access · hybridAbstract read
In one paragraph

Article in Monoclonal antibodies in immunodiagnosis and immunotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. A defucosylated anti-PD-L1 monoclonal antibody 13-mGBiochemistry and biophysics reports · 2020
    Article
  3. A cancer-specific anti-podocalyxin monoclonal antibody (60-mGBiochemistry and biophysics reports · 2020
    Article
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yukinari Kato1 Department of Antibody Drug Development, Tohoku University Graduate School of Medicine , Sendai, Japan .
Takuya Mizuno3 Laboratory of Molecular Diagnostics and Therapeutics, Joint Faculty of Veterinary Medicine, Yamaguchi University , Yamaguchi, Japan .
Shinji Yamada1 Department of Antibody Drug Development, Tohoku University Graduate School of Medicine , Sendai, Japan .
Takuro Nakamura1 Department of Antibody Drug Development, Tohoku University Graduate School of Medicine , Sendai, Japan .
Shunsuke Itai1 Department of Antibody Drug Development, Tohoku University Graduate School of Medicine , Sendai, Japan .
Miyuki Yanaka1 Department of Antibody Drug Development, Tohoku University Graduate School of Medicine , Sendai, Japan .
Masato Sano1 Department of Antibody Drug Development, Tohoku University Graduate School of Medicine , Sendai, Japan .
Mika K Kaneko1 Department of Antibody Drug Development, Tohoku University Graduate School of Medicine , Sendai, Japan .
Tohoku University · JPYamaguchi University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Podoplanin (PDPN), a type I transmembrane sialoglycoprotein, is expressed in normal tissues, including lymphatic endothelial cells, pulmonary type I alveolar cells, and renal podocytes. The overexpression of PDPN in cancers is associated with hematogenous metastasis by interactions with the C-type lectin-like receptor 2 (CLEC-2). We have previously reported the development of a mouse monoclonal antibody (mAb) clone, PMab-38 (IgG

Indexed as

AnimalsAntibodies, MonoclonalAntibody-Dependent Cell CytotoxicityCell Line, TumorCHO CellsCricetulusDogsEpitopesFlow CytometryFucoseHumansMembrane GlycoproteinsMiceNeoplasmsPodocytesPodoplaninAntibodies, MonoclonalEpitopesFucoseMembrane GlycoproteinsPdpn protein, mousePodoplaninRecombinant Fusion Proteinsdog podoplanindPDPNmonoclonal antibodymouse-canine chimeric antibody

Identifiers

PMID30362926
PMCPMC6208159
OpenAlexW2898294136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.