Evidence map›Paper›PMID 30362717›Full record

ArticleJournal of the American Chemical Society2018

Spectroscopic and Electronic Structure Study of ETHE1: Elucidating the Factors Influencing Sulfur Oxidation and Oxygenation in Mononuclear Nonheme Iron Enzymes.

Serra Goudarzi, Jeffrey T Babicz, Omer Kabil, Ruma Banerjee, Edward I Solomon

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. A Dinuclear Iron(II) Persulfide Complex Reacts with OJournal of the American Chemical Society · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Influence of the second coordination sphere on OJournal of inorganic biochemistry · 2025
    Article
  7. Article
  8. Mechanism of Intracellular Elemental Sulfur Oxidation inInternational journal of molecular sciences · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Mechanisms of OBiochemistry · 2021
    Article
  16. Article
  17. Article
  18. Geometric and Electronic Structural Contributions to Fe/OBulletin of Japan Society of Coordination Chemistry · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Serra GoudarziDepartment of Chemistry , Stanford University , Stanford , California 94305 , United States.
Jeffrey T BabiczDepartment of Chemistry , Stanford University , Stanford , California 94305 , United States.
Omer KabilDepartment of Biological Chemistry , University of Michigan Medical School , Ann Arbor , Michigan 48109 , United States.
Ruma BanerjeeDepartment of Biological Chemistry , University of Michigan Medical School , Ann Arbor , Michigan 48109 , United States.ORCID 0000-0001-8332-3275
Edward I SolomonDepartment of Chemistry , Stanford University , Stanford , California 94305 , United States.ORCID 0000-0003-0291-3199

Funding

SPECTROSCOPIC STUDIES OF NONHEME IRON ENZYMESR01GM040392 · NIGMS · STANFORD UNIVERSITY · PI SOLOMON, EDWARD I · 1988 to 2021
$8.6M
Sulfide Oxidation and SignalingR35GM130183 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RUMA V BANERJEE · 2019 to 2026
$3.6M
Enzymology of Sulfide OxidationR01GM112455 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BANERJEE, RUMA V · 2014 to 2017
$1.2M
NIGMS NIH HHS R01 GM040392NIGMS NIH HHS R01 GM112455NIGMS NIH HHS R35 GM130183
6 · The paper itself

Abstract

ETHE1 is a member of a growing subclass of nonheme Fe enzymes that catalyzes transformations of sulfur-containing substrates without a cofactor. ETHE1 dioxygenates glutathione persulfide (GSSH) to glutathione (GSH) and sulfite in a reaction which is similar to that of cysteine dioxygenase (CDO), but with monodentate (vs bidentate) substrate coordination and a 2-His/1-Asp (vs 3-His) ligand set. In this study, we demonstrate that GSS

Indexed as

Circular DichroismCysteine DioxygenaseDensity Functional TheoryHumansMitochondrial ProteinsMolecular ConformationNucleocytoplasmic Transport ProteinsOxidation-ReductionOxygenSulfurCysteine DioxygenaseETHE1 protein, humanMitochondrial ProteinsNucleocytoplasmic Transport ProteinsOxygenSulfur

Identifiers

PMID30362717
PMCPMC6221977

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.