Evidence map›Paper›PMID 30362662›Full record

ArticleJournal of the International AIDS Society2018

Internalized HIV stigma, ART initiation and HIV-1 RNA suppression in South Africa: exploring avoidant coping as a longitudinal mediator.

Valerie A Earnshaw, Laura M Bogart, Jean-Philippe Laurenceau, Brian T Chan, Brendan G Maughan-Brown, Janan J Dietrich, Ingrid Courtney, Gugulethu Tshabalala, Catherine Orrell, Glenda E Gray and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the International AIDS Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 2 syntheses or guidelines pooled it, 81 citations in OpenAlex.

  1. The Social, Behavioral, and Ethical Modalities of COVID-19 on HIV Care in South Africa: A Systematic Review.International journal of environmental research and public health · 2022
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  11. Why Are They Leaving? Factors Associated With Attrition After Testing Among Young South Africans Recently Diagnosed With HIV: An Observational Study.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025
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  18. Effective Messages to Reduce Stigma among People Newly Diagnosed with HIV during Rapid ART Initiation.International journal of environmental research and public health · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 2 countries.

Valerie A EarnshawDepartment of Human Development and Family Sciences, University of Delaware, Newark, DE, USA.ORCID 0000-0002-4147-3301
Laura M BogartRAND Corporation, Santa Monica, CA, USA.
Jean-Philippe LaurenceauDepartment of Psychological & Brain Sciences, University of Delaware, Newark, DE, USA.
Brian T ChanDepartment of Medicine, Brigham and Women's Hospital, Boston, MA, USA.ORCID 0000-0002-6971-3039
Brendan G Maughan-BrownSouthern Africa Labour and Development Research Unit, University of Cape Town, Rondebosch, Cape Town, South Africa.ORCID 0000-0002-7606-8744
Janan J DietrichPerinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Ingrid CourtneyDesmond Tutu HIV Centre, IDM and Department of Medicine, University of Cape Town, Cape Town, South Africa.
Gugulethu TshabalalaPerinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Catherine OrrellDesmond Tutu HIV Centre, IDM and Department of Medicine, University of Cape Town, Cape Town, South Africa.
Glenda E GrayPerinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
David R BangsbergOregon Health & Science University-Portland State University School of Public Health, Portland, OR, USA.
Ingrid T KatzDepartment of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Brigham and Women's Hospital · USDesmond Tutu HIV Foundation · ZAUniversity of Delaware · USUniversity of the Witwatersrand · ZAPortland State University · USRAND Corporation · USSouth African Medical Research Council · ZAUniversity of Cape Town · ZA

Funding

UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RAPHAEL J LANDOVITZ · 1997 to 2026
$53.5M
HIV Treatment Refusal Among Adults Presenting for Testing in Soweto, South AfricaK23MH097667 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI KATZ, INGRID T. · 2012 to 2016
$922k
Syndemics and Loss From the HIV Care Continuum in IndiaK23MH110338 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI CHAN, BRIAN TAN · 2017 to 2020
$783k
Understanding and Addressing Disclosure to Members of Social Networks among People Recovering from Substance Use DisordersK01DA042881 · NIDA · UNIVERSITY OF DELAWARE · PI EARNSHAW, VALERIE ANN · 2017 to 2020
$756k
NIDA NIH HHS K01 DA042881NIMH NIH HHS K23 MH097667NIMH NIH HHS K23 MH110338NIMH NIH HHS P30 MH058107
6 · The paper itself

Abstract

introductionCross-sectional evidence suggests that internalized HIV stigma is associated with lower likelihoods of antiretroviral therapy (ART) initiation and HIV-1 RNA suppression among people living with HIV (PLWH). This study examined these associations with longitudinal data spanning the first nine months following HIV diagnosis and explored whether avoidant coping mediates these associations.

methodsLongitudinal data were collected from 398 South African PLWH recruited from testing centres in 2014 to 2015. Self-report data, including internalized stigma and avoidant coping (denying and distracting oneself from stressors), were collected one week and three months following HIV diagnosis. ART initiation at six months and HIV-1 RNA at nine months were extracted from the South Africa National Health Laboratory Service database. Two path analyses were estimated, one testing associations between internalized stigma, avoidant coping and ART initiation, and the other testing associations between internalized stigma, avoidant coping and HIV-1 RNA suppression.

resultsParticipants were 36 years old, on average, and 63% identified as female, 18% as Zulu and 65% as Xhosa. The two path models fit the data well (ART initiation outcome: X

conclusionsInternalized stigma experienced soon after HIV diagnosis predicted lower likelihood of ART initiation and HIV-1 RNA suppression over the first year following HIV diagnosis. Avoidant coping played a role in these associations, suggesting that PLWH who internalize stigma engage in greater avoidant coping, which in turn worsens medication- and health-related outcomes. Interventions are needed to address internalized stigma and avoidant coping soon after HIV diagnosis to enhance treatment efforts during the first year after HIV diagnosis.

Indexed as

Adaptation, PsychologicalSocial StigmaAdultAnti-HIV AgentsCross-Sectional StudiesFemaleHIV-1HIV InfectionsHumansMaleMiddle AgedPregnancySouth AfricaAnti-HIV Agentsantiretroviral therapycopingHIVSouth Africastigma

Identifiers

PMID30362662
PMCPMC6202800
OpenAlexW2898084424

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.