Evidence map›Paper›PMID 30362318›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2018

The Role of Single Voxel MR Spectroscopy, T2 Relaxation Time and Apparent Diffusion Coefficient in Determining the Cellularity of Brain Tumors by MATLAB Software

Jamil Abdolmohammadi, Fariborz Faeghi, Douman Arefan, Alireza Zali, Hamidreza Haghighatkhah, Jamal Amiri

Open access · greenAbstract read
In one paragraph

Article in Asian Pacific journal of cancer prevention : APJCP, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jamil AbdolmohammadiDepartment of Radiology, Faculty of Paramedical Sciences, Kurdistan University of Medical Sciences, Sanandaj, Iran. Email: Amirijamal123@gmail.com
Fariborz Faeghi
Douman Arefan
Alireza Zali
Hamidreza Haghighatkhah
Jamal Amiri
Kurdistan University of Medical Sciences · IRShahid Beheshti University · IRShahid Beheshti University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Brain tumors if timely diagnosed are sure to be treated through shorter processes. MRI amongst others is of Para clinical methods greatly effective in diagnosis phase. Diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) maps provide some information that could reflect tissue cellularity. Neurosurgeons, in particular to detect the tumor cellularity, must send the specimens taken through biopsy to the pathology unit. This study is aimed at determining the tumor cellularity in brain. Materials and Methods: In this cross-sectional study, 32 patients (18 males and 14 females of the range 18 – 77 y/o) between April 2014 and February 2016 who were referred to the neurosurgery department of Shohada-E Tajrish Hospital of Tehran participated. Imaging was made using single voxel MR Spectroscopy, ADC and T2W Multi Echo Pulse Sequence in addition to routine pulse sequences and the images were analyzed using MATLAB software to determine the cellularity of brain tumors in comparison to the biopsy. Results: findings showed that by decreasing T2 relaxation time, the amount of ADC, N-Acetyl Aspartate (NAA) and also, increase Choline metabolite, lead to registering tumors in the lower class on the designed table and these tumors have a higher degree of consistency and cellularity. T2 Relaxation time, the tumors will stand at higher class on the designed table. Also the results indicated that 85% diagnostic weight of T2 relaxation time and 83% diagnostic weight of ADC compared with biopsy could reveal the brain tumor cellularity (P>0.05). Conclusion: some cellular metabolite changes such as NAA and Choline, ADC value and T2 relaxation time feature could effectively be used to distinguish and illustrate the degree of cellularity of brain tumors especially Intra-axial brain tumors (with about 85%. vs. biopsy). We recommend to more data should be used to increase the accuracy percentage of this technique.

Indexed as

AdolescentAdultAgedAspartic AcidBiopsyBrainBrain NeoplasmsCholineCreatineCross-Sectional StudiesDiffusion Magnetic Resonance ImagingFemaleHumansMagnetic Resonance SpectroscopyMaleMiddle AgedAspartic AcidCholineCreatineN-acetylaspartateBrain tumorMATLAB softwareMRIMRST2 relaxation time

Identifiers

PMID30362318
PMCPMC6291043
OpenAlexW2891189103

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.