Evidence map›Paper›PMID 30362188›Full record

ArticleThe European journal of neuroscience2018

Mutations in the guanylate cyclase gcy-28 neuronally dissociate naïve attraction and memory retrieval.

Naijin Li, Derek van der Kooy

Abstract read
PubMed Publisher
In one paragraph

Article in The European journal of neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Naijin LiThe Donnelly Centre for Cellular and Biomolecular Research, Toronto, Ontario, Canada.ORCID 0000-0002-6361-2552
Derek van der KooyThe Donnelly Centre for Cellular and Biomolecular Research, Toronto, Ontario, Canada.ORCID 0000-0001-9927-9432
University of Toronto · CA

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

The molecules and mechanisms that are involved in the acquisition, storage, and retrieval of memories in many organisms are unclear. To investigate these processes, we use the nematode worm Caenorhabditis elegans, which is attracted naïvely to the odorant benzaldehyde but learns to avoid it after paired exposure with starvation. Mutations in the receptor-like guanylate cyclase GCY-28 have previously been thought to result in a behavioral switch in the primary chemosensory neuron AWC

Indexed as

AnimalsBehavior, AnimalCaenorhabditis elegansCaenorhabditis elegans ProteinsGuanylate CyclaseInterneuronsLearningMembrane ProteinsMemoryMutationNeuronsSignal TransductionCaenorhabditis elegans ProteinsGCY-28 protein, C elegansGuanylate CyclaseMembrane Proteinsassociative learningC. eleganschemosensationolfactionsensory integration

Identifiers

PMID30362188
OpenAlexW2898275828

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.