ArticleClinical pharmacology and therapeutics2019
Pediatric Drug-Drug Interaction Studies: Barriers and Opportunities.
Article in Clinical pharmacology and therapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Development of an Empirical Approach for the Prediction of Cytochrome P450-Based Drug-Drug Interactions in Pediatric Patients.Pharmaceuticals (Basel, Switzerland) · 2026Article
- PQRI Workshop: Model-Informed Drug Development (MIDD) Approaches in Pediatric Formulation Development.The AAPS journal · 2026Article
- Evaluation of potential drug-drug interactions in the neonatal intensive care unit with two different decision support software: a retrospective study.BMC pediatrics · 2025Article
- PBPK Modeling to Support Bioavailability and Bioequivalence Assessment in Pediatric Populations.Pharmaceutical research · 2025Article
- Potential and challenges in application of physiologically based pharmacokinetic modeling in predicting diarrheal disease impact on oral drug pharmacokinetics.Drug metabolism and disposition: the biological fate of chemicals · 2025Review
- Drug-Drug Interactions Involving High-Alert Medications that Lead to Interaction-Associated Symptoms in Pediatric Intensive Care Patients: A Retrospective Study.Paediatric drugs · 2024Article
- Membrane transporters in drug development and as determinants of precision medicine.Nature reviews. Drug discovery · 2024Review
- Major Drug-Drug Interaction Exposure Among Medicaid-Insured Children in the Outpatient Setting.Pediatrics · 2024Article
- Increasing application of pediatric physiologically based pharmacokinetic models across academic and industry organizations.CPT: pharmacometrics & systems pharmacology · 2022Article
- Model-Based Drug-Drug Interaction Extrapolation Strategy From Adults to Children: Risdiplam in Pediatric Patients With Spinal Muscular Atrophy.Clinical pharmacology and therapeutics · 2021Article
- Physiologically Based Pharmacokinetic Modeling of Meropenem in Preterm and Term Infants.Clinical pharmacokinetics · 2021Article
- Pediatric Drug-Drug Interaction Evaluation: Drug, Patient Population, and Methodological Considerations.Journal of clinical pharmacology · 2021Review
- A whole of population retrospective observational study on the rates of polypharmacy in New Zealand 2014 to 2018 Polypharmacy in New Zealand: What is the current status?Health science reports · 2021Article
- The Influence of Haemostatic System Maturation on the Dose-Response Relationship of Unfractionated Heparin.Clinical pharmacokinetics · 2021Article
- Supportive care medications coinciding with chemotherapy among children with hematologic malignancy.Leukemia & lymphoma · 2020Article
- Prediction of Clearance in Children from Adults Following Drug-Drug Interaction Studies: Application of Age-Dependent Exponent Model.Drugs in R&D · 2020Article
- Evaluation of potential drug-drug interactions in a pediatric population.Turk pediatri arsivi · 2020Article
- Incorporating Ontogeny in Physiologically Based Pharmacokinetic Modeling to Improve Pediatric Drug Development: What We Know About Developmental Changes in Membrane Transporters.Journal of clinical pharmacology · 2019Review
- Drug-Drug Interactions of Infectious Disease Treatments in Low-Income Countries: A Neglected Topic?Clinical pharmacology and therapeutics · 2019Review
- Implementation of a Physiologically Based Pharmacokinetic Modeling Approach to Guide Optimal Dosing Regimens for Imatinib and Potential Drug Interactions in Paediatrics.Frontiers in pharmacology · 2019Article
Corrections and comments
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Authors and funding
4 authors.
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Abstract
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.