ArticleJournal of microbiology (Seoul, Korea)2018
Characterization of the velvet regulators in Aspergillus flavus.
Article in Journal of microbiology (Seoul, Korea), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 50 citations in OpenAlex.
- Characterization of velvet family proteins regulating fungal development and virulence in the peach shoot blight fungusVirulence · 2026Article
- Members of Velvet Complex FpVeA and FpVelB Regulate Asexual Development, Fumonisin Biosynthesis and Virulence inFoods (Basel, Switzerland) · 2025Article
- Regulation ofToxins · 2025Article
- Species-specific gene regulatory network rewiring mediated by the GATA-type regulator NsdD inmBio · 2025Article
- Role of the LAMMER kinase LkhA in fungal development and aflatoxin production in Aspergillus flavus.Journal of microbiology (Seoul, Korea) · 2025Article
- Inhibition Mechanism ofFoods (Basel, Switzerland) · 2025Article
- UvVelC is important for conidiation and pathogenicity in the rice false smut pathogenVirulence · 2024Article
- Beyond morphogenesis and secondary metabolism: function of Velvet proteins and LaeA in fungal pathogenesis.Applied and environmental microbiology · 2024Review
- The Velvet transcription factor PnVeA regulates necrotrophic effectors and secondary metabolism in the wheat pathogen Parastagonospora nodorum.BMC microbiology · 2024Article
- Involvement of LaeA and Velvet Proteins in Regulating the Production of Mycotoxins and Other Fungal Secondary Metabolites.Journal of fungi (Basel, Switzerland) · 2024Review
- Rhein Inhibits Cell Development and Aflatoxin Biosynthesis via Energy Supply Disruption and ROS Accumulation inToxins · 2024Article
- An environmental isolate ofFrontiers in microbiology · 2024Article
- Regulation of Fungal Morphogenesis and Pathogenicity ofJournal of fungi (Basel, Switzerland) · 2023Article
- Light regulation of secondary metabolism in fungi.Journal of biological engineering · 2023Review
- Estragole Inhibits Growth and Aflatoxin Biosynthesis ofMicrobiology spectrum · 2023Article
- Histone 2-Hydroxyisobutyryltransferase Encoded byToxins · 2022Article
- Review
- Regulation of Conidiogenesis inCells · 2022Review
- Recent advances in metabolic regulation and bioengineering of gibberellic acid biosynthesis in Fusarium fujikuroi.World journal of microbiology & biotechnology · 2022Review
- The Zinc Finger Transcription Factor BbCmr1 Regulates Conidium Maturation in Beauveria bassiana.Microbiology spectrum · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fungal development and secondary metabolism are closely associated via the activities of the fungal NK-kB-type velvet regulators that are highly conserved in filamentous fungi. Here, we investigated the roles of the velvet genes in the aflatoxigenic fungus Aspergillus flavus. Distinct from other Aspergillus species, the A. flavus genome contains five velvet genes, veA, velB, velC, velD, and vosA. The deletion of velD blocks the production of aflatoxin B1, but does not affect the formation of sclerotia. Expression analyses revealed that vosA and velB mRNAs accumulated at high levels during the late phase of asexual development and in conidia. The absence of vosA or velB decreased the content of conidial trehalose and the tolerance of conidia to the thermal and UV stresses. In addition, double mutant analyses demonstrated that VosA and VelB play an inter-dependent role in trehalose biosynthesis and conidial stress tolerance. Together with the findings of previous studies, the results of the present study suggest that the velvet regulators play the conserved and vital role in sporogenesis, conidial trehalose biogenesis, stress tolerance, and aflatoxin biosynthesis in A. flavus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.