ArticleEuropean archives of psychiatry and clinical neuroscience2020
Age effects on basic symptoms in the community: A route to gain new insight into the neurodevelopment of psychosis?
Article in European archives of psychiatry and clinical neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Metacognitive beliefs in individuals at risk for psychosis: a systematic review and meta-analysis of sex differences.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2020Pooled it
- Basic symptoms of psychosis-from historical foundations to current evidence.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2026Review
- Psychotic Vulnerability in Adolescents With Obsessive-Compulsive Disorder: First Longitudinal Evidence From a Prospective Pilot Study.Early intervention in psychiatry · 2026Article
- Subclinical and attenuated negative symptoms in the prediction of psychosis in children and adolescents: sample composition matters.European child & adolescent psychiatry · 2026Article
- The relationship between stress and clinical high-risk symptoms of psychosis in daily life: impact of contemporaneous paths on cross-lagged effects.Psychological medicine · 2025Article
- Investigating the associations between personality functioning, cognitive biases, and (non-)perceptive clinical high-risk symptoms of psychosis in the community.European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
- Three-year course of clinical high-risk symptoms for psychosis in the community: a latent class analysis.Epidemiology and psychiatric sciences · 2025Article
- Psychotic symptoms in Chinese patients with somatic symptom disorder: prevalence, risk factors, and associated conditions.Frontiers in psychiatry · 2025Article
- Clinical and neurocognitive profiles of a combined clinical high risk for psychosis and clinical control sample: latent class analysis.BJPsych open · 2024Article
- Article
- Exploring the complex relationships between coping strategies, locus of control and self-esteem with psychopathology: structural equation modeling with a special focus on clinical high-risk of psychosis.European psychiatry : the journal of the Association of European Psychiatrists · 2023Article
- An ecological momentary assessment study of age effects on perceptive and non-perceptive clinical high-risk symptoms of psychosis.European child & adolescent psychiatry · 2023Article
- The role of mentalizing in the relationship between schizotypal personality traits and state signs of psychosis risk captured by cognitive and perceptive basic symptoms.Frontiers in psychiatry · 2023Article
- The heterogeneity of attenuated and brief limited psychotic symptoms: association of contents with age, sex, country, religion, comorbidities, and functioning.Frontiers in psychiatry · 2023Article
- The impact of visual dysfunctions in recent-onset psychosis and clinical high-risk state for psychosis.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Article
- Spontaneous discontinuation of distressing auditory verbal hallucinations in a school-based sample of adolescents: a longitudinal study.European child & adolescent psychiatry · 2020Article
- Effects of age and sex on clinical high-risk for psychosis in the community.World journal of psychiatry · 2020Article
- Basic Symptoms Are Associated With Age in Patients With a Clinical High-Risk State for Psychosis: Results From the PRONIA Study.Frontiers in psychiatry · 2020Article
- Basic symptoms in offspring of parents with mood and psychotic disorders.BJPsych open · 2019Article
- Psychosis and Schizophrenia-Spectrum Personality Disorders Require Early Detection on Different Symptom Dimensions.Frontiers in psychiatry · 2019Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Reports of limited clinical significance of attenuated psychotic symptoms before age 15/16 indicate an important role of neurodevelopment in the early detection of psychoses. Therefore, we examined if age also exerts an influence on the prevalence and clinical significance of the 14 cognitive and perceptive basic symptoms (BS) used in psychosis-risk criteria and conceptualized as the most direct self-experienced expression of neurobiological aberrations. A random representative general population sample of the Swiss canton Bern (N = 689, age 8-40 years, 06/2011-05/2014) was interviewed for BS, psychosocial functioning, and current mental disorder. BS were reported by 18% of participants, mainly cognitive BS (15%). In regression analyses, age affected perceptive and cognitive BS differently, indicating an age threshold for perceptive BS in late adolescence (around age 18) and for cognitive BS in young adulthood (early twenties)-with higher prevalence, but a lesser association with functional deficits and the presence of mental disorder in the below-threshold groups. Thereby, interaction effects between age and BS on functioning and mental disorder were commonly stronger than individual effects of age and BS. Indicating support of the proposed "substrate-closeness" of BS, differential age effects of perceptual and cognitive BS seem to follow normal brain maturation processes, in which they might occur as infrequent and temporary non-pathological disturbances. Their persistence or occurrence after conclusion of main brain maturation processes, however, might signify aberrant maturation or neurodegenerative processes. Thus, BS might provide important insight into the pathogenesis of psychosis and into differential neuroprotective or anti-inflammatory targets.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.