Evidence map›Paper›PMID 30361793›Full record

Trial reportClinical oral investigations2019

Effect of photobiomodulation with low-level laser therapy combined with potassium nitrate on controlling post-bleaching tooth sensitivity: clinical, randomized, controlled, double-blind, and split-mouth study.

Brennda de Paula, Cristiane Alencar, Mariángela Ortiz, Roberta Couto, Jesuína Araújo, Cecy Silva

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Clinical oral investigations, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05309967 (Effect of Glutaraldehyde-based Desensitizer in the Control of Tooth Sensitivity and Tooth Color Post- Whitening), which is not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05309967 nacompletednot on this mapstarted 2021, after this paper: background citation

Effect of Glutaraldehyde-based Desensitizer in the Control of Tooth Sensitivity and Tooth Color Post- Whitening : a Randomized, Single Blind and Split Mouth Clinical Trial.

TypeinterventionalSponsorUniversidade Federal do ParaRan2021 to 2023Enrolled25ConditionsDentin SensitivityArmsGLUMA DESINSITIZER, PLACEBO
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
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  7. Article
  8. Article
  9. Photobiomodulation therapy.JADA foundational science · 2025
    Review
  10. Review
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Brennda de PaulaGraduate Program in Dentistry, Federal University of Pará, Belém, PA, Brazil.
Cristiane AlencarGraduate Program in Dentistry, Federal University of Pará, Belém, PA, Brazil.
Mariángela OrtizGraduate Program in Dentistry, Federal University of Pará, Belém, PA, Brazil.
Roberta CoutoGraduate Program in Dentistry, Federal University of Pará, Belém, PA, Brazil.
Jesuína AraújoSchool of Dentistry, Federal University of Pará, Belém, PA, Brazil.
Cecy SilvaGraduate Program in Dentistry, Federal University of Pará, Belém, PA, Brazil. cecymsilva@gmail.com.ORCID http://orcid.org/0000-0002-7870-8848
Universidade Federal do Pará · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the effect of photobiomodulation with low-level laser therapy (PBM-LLLT) combined with 5% potassium nitrate (KNO MATERIALS AND

methodsFifty volunteers were selected based on the inclusion and exclusion criteria and were randomly allocated into four groups: G1 (control): placebo gel application, 35% hydrogen peroxide bleaching (HP35) and mock PBM-LLLT without light emission; G2: placebo gel application, bleaching with HP35 and PBM-LLLT; G3: application of KNO

resultsThe intragroup evaluation showed significant differences among the evaluation times in all groups (p ≤ 0.05). The highest pain sensitivity levels were recorded on the 1st, 8th, and 15th days. In G1, TS manifested for up to 3 days after each bleaching session, while G2, G3, and G4 presented TS only on the days of the bleaching sessions. Intergroup analysis showed that TS manifestation differed significantly between G1 and the other groups (p ≤ 0.05) but did not differ significantly among G2, G3, and G4 (p ≥ 0.05).

conclusionPBM-LLLT and KNO CLINICAL RELEVANCE: The effect of PBM-LLLT combined with KNO

Indexed as

Low-Level Light TherapyAdultDentin SensitivityDouble-Blind MethodFemaleHumansHydrogen PeroxideMaleNitratesPotassium CompoundsTooth BleachingTooth Bleaching AgentsTreatment OutcomeYoung AdultHydrogen PeroxideNitratesPotassium Compoundspotassium nitrateTooth Bleaching AgentsDentin desensitizersLow-level laser therapyRandomized clinical trialTooth bleachingTooth sensitivity

Identifiers

PMID30361793
OpenAlexW2898419093

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.