ArticleJournal of molecular evolution2018
A Non-neutral Origin for Error Minimization in the Origin of the Genetic Code.
Article in Journal of molecular evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 12 citations in OpenAlex.
- Little Evidence the Standard Genetic Code Is Optimized for Resource Conservation.Molecular biology and evolution · 2021Article
- The Combinatorial Fusion Cascade to Generate the Standard Genetic Code.Life (Basel, Switzerland) · 2021Article
- The Mutational Robustness of the Genetic Code and Codon Usage in Environmental Context: A Non-Extremophilic Preference?Life (Basel, Switzerland) · 2021Article
- Adaptive Properties of the Genetically Encoded Amino Acid Alphabet Are Inherited from Its Subsets.Scientific reports · 2019Article
- Genetic Code Error Minimization as a Non-Adaptive But Beneficial Trait.Journal of molecular evolution · 2019Article
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1 author at 1 institution in 1 country.
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Abstract
Massey (J Mol Evol 67:510-516, 2008; J Theor Biol 408:237-242, 2016; Nat Comput. https://doi.org/10.1007/s11047-017-9669-3, 2018) claims that the error minimization of the genetic code is derived by means of a neutral process and was not due to the action of natural selection. Here, I argue that this neutralist hypothesis of the origin of error minimization is not based directly on any neutral process but it could be only indirectly. On the contrary, it has been natural selection that has acted during the origin of the genetic code determining the property that similar amino acids are coded by similar codons within the genetic code table.
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