Evidence map›Paper›PMID 30361517›Full record

ArticleScientific reports2018

Women with prolonged nausea in pregnancy have increased risk for depressive symptoms postpartum.

Stavros I Iliadis, Cathrine Axfors, Sara Johansson, Alkistis Skalkidou, Ajlana Mulic-Lutvica

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
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  7. Article
  8. Article
  9. Review
  10. Article
  11. Risk Factors of Prolonged Nausea and Vomiting During Pregnancy.Risk management and healthcare policy · 2020
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Stavros I IliadisDepartment of Women's and Children's Health, Uppsala University, 751 85, Uppsala, Sweden. stavros.iliadis@kbh.uu.se.
Cathrine AxforsDepartment of Women's and Children's Health, Uppsala University, 751 85, Uppsala, Sweden.
Sara JohanssonDepartment of Women's and Children's Health, Uppsala University, 751 85, Uppsala, Sweden.
Alkistis SkalkidouDepartment of Women's and Children's Health, Uppsala University, 751 85, Uppsala, Sweden.ORCID http://orcid.org/0000-0002-4935-7532
Ajlana Mulic-LutvicaDepartment of Women's and Children's Health, Uppsala University, 751 85, Uppsala, Sweden.ORCID http://orcid.org/0000-0003-4394-8769
Uppsala University · SE

Funding

Akademiska Sjukhuset (Uppsala University Hospital) 2012-SkalkidouForskningsrådet för Arbetsliv och Socialvetenskap (Swedish Council for Working Life and Social Research) 2007-1955Sveriges Läkarförbund (Swedish Medical Association) SLS-250581Vetenskapsrådet (Swedish Research Council) 521-2010-3293
6 · The paper itself

Abstract

The aim of this population-based, longitudinal study was to assess the association between nausea and vomiting in pregnancy (NVP) and perinatal depressive symptoms. Pregnant women (N = 4239) undergoing routine ultrasound at gestational week (GW) 17 self-reported on NVP and were divided into those without nausea (G0), early (≤17 GW) nausea without medication (G1), early nausea with medication (G2), and prolonged (>17 GW) nausea (G3). The Edinburgh Postnatal Depression Scale at GW 17 and 32 (cut-off ≥13) and at six weeks postpartum (cut-off ≥12) was used to assess depressive symptoms. Main outcome measures were depressive symptoms at GW 32 and at six weeks postpartum. NVP was experienced by 80.7%. The unadjusted logistic regression showed a positive association between all three nausea groups and depressive symptoms at all time-points. After adjustment, significant associations with postpartum depressive symptoms remained for G3, compared to G0 (aOR = 1.66; 95% CI 1.1-2.52). After excluding women with history of depression, only the G3 group was at higher odds for postpartum depressive symptoms (aOR = 2.26; 95% CI 1.04-4.92). In conclusion, women with prolonged nausea have increased risk of depressive symptoms at six weeks postpartum, regardless of history of depression.

Indexed as

AdultDepression, PostpartumFemaleHumansLogistic ModelsNauseaOdds RatioPregnancyPrevalenceRisk FactorsSwedenVomiting

Identifiers

PMID30361517
PMCPMC6202412
OpenAlexW2897732158

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.