ArticleDrug and alcohol dependence2019
DSM-5 cannabis withdrawal syndrome: Demographic and clinical correlates in U.S. adults.
Article in Drug and alcohol dependence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence of Cannabis Withdrawal Symptoms Among People With Regular or Dependent Use of Cannabinoids: A Systematic Review and Meta-analysis.JAMA network open · 2020Pooled it
- Increased encoding of aversive stimuli by lateral habenula neurons during ΔNature communications · 2026Article
- Identifying and addressing cannabis withdrawal syndrome.Journal of military, veteran and family health · 2026Article
- Psychometric validation of the Cannabis Withdrawal Checklist in a Spanish sample with cannabis use disorder.Frontiers in psychology · 2026Article
- Predictors of effective therapy among individuals with Cannabis Use Disorder: a review of the literature.European archives of psychiatry and clinical neuroscience · 2025Review
- Clinician's perceptions and experiences with tobacco treatment in people who use cannabis: a qualitative study.Substance abuse treatment, prevention, and policy · 2025Observational
- Review
- Enhancing translation: A need to leverage complex preclinical models of addictive drugs to accelerate substance use treatment options.Pharmacology, biochemistry, and behavior · 2024Review
- Patterns of Use and Withdrawal Syndrome in Dual Cannabis and Tobacco Users (DuCATA_GAM-CAT): Protocol for a Mixed Methods Study.JMIR research protocols · 2024Article
- CB1 Receptor Negative Allosteric Modulators as a Potential Tool to Reverse Cannabinoid Toxicity.Molecules (Basel, Switzerland) · 2024Article
- Dimensionality and differential functioning of DSM-5 cannabis use disorder criteria in an online sample of adults with frequent cannabis use.Journal of psychiatric research · 2023Article
- Addressing adolescent substance use with a public health prevention framework: the case for harm reduction.Annals of medicine · 2022Review
- Cannabinoid hyperemesis syndrome and cannabis withdrawal syndrome: a review of the management of cannabis-related syndrome in the emergency department.International journal of emergency medicine · 2022Review
- Development of a computerized adaptive substance use disorder scale for screening, measurement and diagnosis - The CAT-SUD-E.Drug and alcohol dependence reports · 2022Article
- Clinical withdrawal symptom profile of synthetic cannabinoid receptor agonists and comparison of effects with high potency cannabis.Psychopharmacology · 2022Article
- Alcohol withdrawal in past-year drinkers with unhealthy alcohol use: Prevalence, characteristics, and correlates in a national epidemiologic survey.Alcoholism, clinical and experimental research · 2022Article
- Considerations for Cannabinoids in Perioperative Care by Anesthesiologists.Journal of clinical medicine · 2022Review
- Progression of cannabis withdrawal symptoms in people using medical cannabis for chronic pain.Addiction (Abingdon, England) · 2021Article
- Gabapentin attenuates somatic signs of precipitated THC withdrawal in mice.Neuropharmacology · 2021Article
- Trends over time in adult cannabis use: A review of recent findings.Current opinion in psychology · 2021Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundCannabis withdrawal syndrome (CWS) was newly added to the Diagnostic and Statistical Manual of Mental Disorders in its most recent edition, DSM-5. With cannabis use increasing among U.S. adults, information is needed about the prevalence and correlates of DSM-5 CWS in the general population. This study presents nationally representative findings on the prevalence, sociodemographic and clinical correlates of DSM-5 CWS among U.S. adults.
methodParticipants ≥18 years were interviewed in the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III) in 2012-2013. Among the sub-sample of frequent cannabis users in the prior 12 months (≥3 times a week; N = 1527), the prevalence and demographic and clinical correlates of DSM-5 CWS were examined.
resultsIn frequent cannabis users, the prevalence of CWS was 12.1%. The most common withdrawal symptoms among those with CWS were nervousness/anxiety (76.3%), hostility (71.9%), sleep difficulty (68.2%) and depressed mood (58.9%). CWS was associated with significant disability (p < 0.001), and with mood disorders (adjusted odds ratios [aOR] = 1.9-2.6), anxiety disorders (aOR = 2.4-2.5), personality disorders (aOR = 1.7-2.2) and family history of depression (aOR = 2.5) but not personal history of other substance use disorders or family history of substance use problems.
conclusionsCWS is highly comorbid and disabling. Its shared symptoms with depressive and anxiety disorders call for clinician awareness of CWS and the factors associated with it to promote more effective treatment among frequent cannabis users.
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