Evidence map›Paper›PMID 30360467›Full record

ReviewInternational journal of molecular sciences2018

Arachidonic Acid Metabolites in Cardiovascular and Metabolic Diseases.

Thomas Sonnweber, Alex Pizzini, Manfred Nairz, Günter Weiss, Ivan Tancevski

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 226 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
226citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

226 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  14. Recipient plasma metabolomics as a predictor of heart transplant severe primary graft dysfunction.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026
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166 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thomas SonnweberDepartment of Internal Medicine II, Medical University Innsbruck, Innsbruck 6020, Austria. Thomas.Sonnweber@i-med.ac.at.ORCID 0000-0002-5080-386X
Alex PizziniDepartment of Internal Medicine II, Medical University Innsbruck, Innsbruck 6020, Austria. Alex.Pizzini@i-med.ac.at.
Manfred NairzDepartment of Internal Medicine II, Medical University Innsbruck, Innsbruck 6020, Austria. Manfred.Nairz@i-med.ac.at.
Günter WeissDepartment of Internal Medicine II, Medical University Innsbruck, Innsbruck 6020, Austria. guenter.weiss@i-med.ac.at.ORCID 0000-0003-0709-2158
Ivan TancevskiDepartment of Internal Medicine II, Medical University Innsbruck, Innsbruck 6020, Austria. Ivan.Tancevski@i-med.ac.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipid and immune pathways are crucial in the pathophysiology of metabolic and cardiovascular disease. Arachidonic acid (AA) and its derivatives link nutrient metabolism to immunity and inflammation, thus holding a key role in the emergence and progression of frequent diseases such as obesity, diabetes, non-alcoholic fatty liver disease, and cardiovascular disease. We herein present a synopsis of AA metabolism in human health, tissue homeostasis, and immunity, and explore the role of the AA metabolome in diverse pathophysiological conditions and diseases.

Indexed as

AnimalsArachidonic AcidCardiovascular DiseasesCholesterolEicosanoidsHumansLipid MetabolismNon-alcoholic Fatty Liver DiseaseObesityArachidonic AcidCholesterolEicosanoidsarachidonic acidatherosclerosiscardiovascular diseasecholesteroldiabeteseicosanoidsmetabolic diseasenonalcoholic fatty liver diseaseobesity

Identifiers

PMID30360467
PMCPMC6274989

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.