Evidence map›Paper›PMID 30360404›Full record

ArticleMolecules (Basel, Switzerland)2018

Nuciferine Inhibits Proinflammatory Cytokines via the PPARs in LPS-Induced RAW264.7 Cells.

Chao Zhang, Jianjun Deng, Dan Liu, Xingxia Tuo, Yan Yu, Haixia Yang, Nanping Wang

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04148677 (The Role of Protopine Associated With Nuciferine), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04148677 unknown statusnot on this mapstarted 2019, after this paper: background citation

The Role of Protopine Associated With Nuciferine (Protoves M1® Syrup) in Controlling Adverse Event During HIVEC® Instillations

TypeobservationalSponsorCardarelli HospitalRan2019 to 2020Enrolled100ConditionsBladder Cancer, LUTS, PainArmsProtoves M1®
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Preventive Effect of Nuciferine on HMolecules (Basel, Switzerland) · 2022
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. The Effect of Sacred Lotus (Molecules (Basel, Switzerland) · 2020
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Chao ZhangDepartment of Nutrition and Food Safety, College of Public Health, Xi'an Jiaotong University, Xi'an 710061, China. zhangchao9277@163.com.
Jianjun DengShaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Xi'an 710069, China. dengjianjun@nwu.edu.cn.
Dan LiuDepartment of Nutrition and Food Safety, College of Public Health, Xi'an Jiaotong University, Xi'an 710061, China. liudan940305@163.com.
Xingxia TuoDepartment of Nutrition and Food Safety, College of Public Health, Xi'an Jiaotong University, Xi'an 710061, China. yyyyyy_214@163.com.
Yan YuDepartment of Nutrition and Food Safety, College of Public Health, Xi'an Jiaotong University, Xi'an 710061, China. yuyan@mail.xjtu.edu.cn.
Haixia YangDepartment of Nutrition and Food Safety, College of Public Health, Xi'an Jiaotong University, Xi'an 710061, China. yanghx@xjtu.edu.cn.ORCID 0000-0002-4410-9257
Nanping WangCardiovascular Research Center, Xi'an Jiaotong University, Xi'an 710061, China. nanpingwang2003@yahoo.com.
Xi'an Jiaotong University · CNDalian Medical University · CNNorthwest University · CN

Funding

China Postdoctoral Science Foundation 2016M602833National Natural Science Foundation of China 21676212Shaanxi Postdoctoral Science Foundation 2017BSHTDZZ14Shaanxi Provincial Scientific Technology Research and Development Program 2018KJXX-017
6 · The paper itself

Abstract

Inflammation is important and has been found to be an underlying cause in many acute and chronic human diseases. Nuciferine, a natural alkaloid containing an aromatic ring, is found in the

Indexed as

AnimalsAnti-Inflammatory AgentsAporphinesCell SurvivalCytokinesEnzyme ActivationInflammation MediatorsLipopolysaccharidesMacrophagesMicePPAR alphaPPAR gammaRAW 264.7 CellsAnti-Inflammatory AgentsAporphinesCytokinesInflammation MediatorsLipopolysaccharidesnuciferinePPAR alphaPPAR gammaIL-6inflammationnuciferinePPARsTNF-α

Identifiers

PMID30360404
PMCPMC6222486
OpenAlexW2896129774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.