Evidence map›Paper›PMID 30360380›Full record

ArticleMolecules (Basel, Switzerland)2018

Isolation of Tricin as a Xanthine Oxidase Inhibitor from Sweet White Clover (

Xiao-Xiao Liu, Shi-Wei Sun, Wen-Jing Yuan, Hua Gao, Yue-Yue Si, Kun Liu, Shuang Zhang, Yang Liu, Wei Wang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Xiao-Xiao LiuDepartment of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 266021, China. lxxlxx19910924@163.com.
Shi-Wei SunDepartment of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 266021, China. sunsw@qdu.edu.cn.
Wen-Jing YuanDepartment of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 266021, China. yuanwenjingqdu@163.com.
Hua GaoDepartment of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 266021, China. gaohuaqy@126.com.
Yue-Yue SiDepartment of Drug Metabolism and Analysis, School of Pharmacy, Qingdao University, Qingdao 266021, China. syy2016qd@163.com.
Kun LiuDepartment of Drug Metabolism and Analysis, School of Pharmacy, Qingdao University, Qingdao 266021, China. kunliu62@126.com.
Shuang ZhangDepartment of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 266021, China. qdeduzhangshuang@163.com.
Yang LiuDepartment of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 266021, China. buckuper@163.com.
Wei WangDepartment of Natural Medicine and Pharmacognosy, School of Pharmacy, Qingdao University, Qingdao 266021, China. w.w.wangwei@263.net.ORCID 0000-0003-0852-4047
Qingdao University · CN

Funding

Program for Science and Technology Development of Shandong Province, China 2014GSF119025Shandong Provincial Natural Science Foundation, China ZR2016HB22
6 · The paper itself

Abstract

Xanthine oxidase, an enzyme present in significant levels in the intestine and liver, metabolizes hypoxanthine to xanthine and xanthine to uric acid in the purine catabolic pathway. An inhibitory compound acting against xanthine oxidase was isolated from sweet white clover (

Indexed as

Chromatography, High Pressure LiquidEnzyme ActivationEnzyme InhibitorsFlavonoidsMelilotusModels, MolecularMolecular ConformationPlant ExtractsProtein BindingSolubilityStructure-Activity RelationshipXanthine OxidaseEnzyme InhibitorsFlavonoidsPlant ExtractstricinXanthine OxidaseGramineae speciesMelilotus albus Medic. ex Desrtricinxanthine oxidase

Identifiers

PMID30360380
PMCPMC6222886
OpenAlexW2896284690

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.