Evidence map›Paper›PMID 30360357›Full record

ArticleInternational journal of molecular sciences2018

Type-II tRNAs and Evolution of Translation Systems and the Genetic Code.

Yunsoo Kim, Bruce Kowiatek, Kristopher Opron, Zachary F Burton

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Evolution of the genetic code.Transcription · 2021
    Review
  8. Article
  9. The 3-Minihelix tRNA Evolution Theorem.Journal of molecular evolution · 2020
    Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Ribosome Structure, Function, and Early Evolution.International journal of molecular sciences · 2018
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Yunsoo KimUniversity of Michigan, Ann Arbor, MI 48109, USA. yunsoo@umich.edu.ORCID 0000-0003-3433-4474
Bruce KowiatekBlue Ridge Community and Technical College, Martinsburg, WV 25403, USA. BKOWIATE@blueridgectc.edu.ORCID 0000-0001-9108-5625
Kristopher OpronBioinformatics Core, University of Michigan, Ann Arbor, MI 48109, USA. kopron@gmail.com.
Zachary F BurtonDepartment of Biochemistry and Molecular Biology, Michigan State University, E. Lansing, MI 48824, USA. burton@msu.edu.
University of Michigan · USBlue Ridge Community and Technical College · USMichigan State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Because tRNA is the core biological intellectual property that was necessary to evolve translation systems, tRNAomes, ribosomes, aminoacyl-tRNA synthetases, and the genetic code, the evolution of tRNA is the core story in evolution of life on earth. We have previously described the evolution of type-I tRNAs. Here, we use the same model to describe the evolution of type-II tRNAs, with expanded V loops. The models are strongly supported by inspection of typical tRNA diagrams, measuring lengths of V loop expansions, and analyzing the homology of V loop sequences to tRNA acceptor stems. Models for tRNA evolution provide a pathway for the inanimate-to-animate transition and for the evolution of translation systems, the genetic code, and cellular life.

Indexed as

Evolution, MolecularGenetic CodeNucleic Acid ConformationRNA, TransferRNA, Transferevolution of translation systemsevolution of tRNAminihelicestype-II tRNAV loopV loop-acceptor stem homology

Identifiers

PMID30360357
PMCPMC6214036
OpenAlexW2897404217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.