ArticleACS applied materials & interfaces2018
Gated Single-Molecule Transport in Double-Barreled Nanopores.
Article in ACS applied materials & interfaces, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- From Enzymatic Dopamine Biosensors to OECT Biosensors of Dopamine.Biosensors · 2023Review
- Design of a Current Sensing System with TIA Gain of 160 dBΩ and Input-Referred Noise of 1.8 pASensors (Basel, Switzerland) · 2023Article
- The New Era of High-Throughput Nanoelectrochemistry.Analytical chemistry · 2023Review
- Single-Molecule Binding Assay Using Nanopores and Dimeric NP Conjugates.Advanced materials (Deerfield Beach, Fla.) · 2021Article
- Needle-type organic electrochemical transistor for spatially resolved detection of dopamine.Mikrochimica acta · 2020Article
- Fabrication and Characterization of Micro-Nano Electrodes for Implantable BCI.Micromachines · 2019Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Single-molecule methods have been rapidly developing with the appealing prospect of transforming conventional ensemble-averaged analytical techniques. However, challenges remain especially in improving detection sensitivity and controlling molecular transport. In this article, we present a direct method for the fabrication of analytical sensors that combine the advantages of nanopores and field-effect transistors for simultaneous label-free single-molecule detection and manipulation. We show that these hybrid sensors have perfectly aligned nanopores and field-effect transistor components making it possible to detect molecular events with up to near 100% synchronization. Furthermore, we show that the transport across the nanopore can be voltage-gated to switch on/off translocations in real time. Finally, surface functionalization of the gate electrode can also be used to fine tune transport properties enabling more active control over the translocation velocity and capture rates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.