Evidence map›Paper›PMID 30359689›Full record

Observational studyJournal of cardiac failure2018

Heart Failure Etiologies and Challenges to Care in the Developing World: An Observational Study in the Democratic Republic of Congo.

Didier Malamba-Lez, Dophra Ngoy-Nkulu, Paul Steels, Désiré Tshala-Katumbay, Wilfried Mullens

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of cardiac failure, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Review
  7. Five cases of Peripartum Cardiomyopathy in Malawi.Malawi medical journal : the journal of Medical Association of Malawi · 2023
    Article
  8. Review
  9. Article
  10. Article
  11. Observational
  12. Genetics of inherited cardiomyopathies in Africa.Cardiovascular diagnosis and therapy · 2020
    Review
  13. Hidden in Heart Failure.European cardiology · 2019
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Didier Malamba-LezDepartment of Internal Medicine, Faculty of Medicine, University of Lubumbashi, Democratic Republic of Congo; Doctoral School for Medicine and Life Sciences, Hasselt University, Diepenbeek, Belgium. Electronic address: didiermalamba@gmail.com.
Dophra Ngoy-NkuluDepartment of Internal Medicine, Faculty of Medicine, University of Lubumbashi, Democratic Republic of Congo.
Paul SteelsBiomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, Diepenbeek, Belgium.
Désiré Tshala-KatumbayDepartment of Neurology and School of Public Health, Oregon Health & Science University, Portland OR, USA.
Wilfried MullensBiomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, Diepenbeek, Belgium; Department of Cardiology, Ziekenhuis Oost-Limburg, Genk, Belgium.

Funding

Toxicodietary and genetic determinants of susceptibility to neurodegenerationR01ES019841 · NIEHS · OREGON HEALTH & SCIENCE UNIVERSITY · PI TSHALA-KATUMBAY, DANIEL DESIRE · 2011 to 2020
$4.6M
NIEHS NIH HHS R01 ES019841
6 · The paper itself

Abstract

backgroundLimited data are available regarding causes and outcomes of heart failure as well as organization of care in the developing world. METHODS AND

resultsWe included consecutive patients diagnosed with heart failure from November 2014 to September 2016 in a university and private hospital of Lubumbashi, Democratic Republic Congo. Baseline data, including echocardiography, were analyzed to determine factors associated with mortality. Cost of hospitalization as well as challenges for care regarding follow-up were determined. A total of 231 patients (56 ± 17 years, 47% men, left ventricular ejection fraction 29 ± 15%, 20% atrial fibrillation) were diagnosed, more during heart failure hospitalizations (69%) than as outpatients (31%). Main risk factors for heart failure included hypertension (59%), chronic kidney disease (51%), alcohol abuse (38%), and obesity (32%). Dilated cardiomyopathy was the most prevalent etiology (48%), with ischemic cardiomyopathy being present in only 4%. In-hospital mortality rate was 19% and associated with an estimated glomerular filtration rate of <60 mL·min

conclusionsPatients admitted for heart failure in DRC have a high incidence of nonischemic cardiomyopathy and present late during their disease, with limited resources being available accounting for a high mortality rate and very high loss to follow-up.

Indexed as

Cardiomyopathy, DilatedDelivery of Health CareDemocratic Republic of the CongoDeveloping CountriesEchocardiographyFemaleFollow-Up StudiesHeart FailureHospital MortalityHumansHypertensionIncidenceMaleMiddle AgedMyocardial IschemiaPrognosischallenges to caredeveloping worldHeart failure

Identifiers

PMID30359689
PMCPMC6635643

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.