Evidence map›Paper›PMID 30359401›Full record

ArticlePloS one2018

Intraframe motion correction for raster-scanned adaptive optics images using strip-based cross-correlation lag biases.

Mehdi Azimipour, Robert J Zawadzki, Iwona Gorczynska, Justin Migacz, John S Werner, Ravi S Jonnal

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Mehdi AzimipourVision Science and Advanced Retinal Imaging Laboratory (VSRI), Department of Ophthalmology and Vision Science, UC Davis Eye Center, Sacramento, CA, United States of America.ORCID 0000-0002-2033-8207
Robert J ZawadzkiVision Science and Advanced Retinal Imaging Laboratory (VSRI), Department of Ophthalmology and Vision Science, UC Davis Eye Center, Sacramento, CA, United States of America.
Iwona GorczynskaDepartment of Physics, Astronomy and Informatics, Nicolaus Copernicus University, Torun, Poland.
Justin MigaczVision Science and Advanced Retinal Imaging Laboratory (VSRI), Department of Ophthalmology and Vision Science, UC Davis Eye Center, Sacramento, CA, United States of America.
John S WernerVision Science and Advanced Retinal Imaging Laboratory (VSRI), Department of Ophthalmology and Vision Science, UC Davis Eye Center, Sacramento, CA, United States of America.
Ravi S JonnalVision Science and Advanced Retinal Imaging Laboratory (VSRI), Department of Ophthalmology and Vision Science, UC Davis Eye Center, Sacramento, CA, United States of America.
University of California, Davis · USNicolaus Copernicus University · PL

Funding

VISION RESEARCH CORE GRANTP30EY012576 · NEI · UNIVERSITY OF CALIFORNIA DAVIS · PI LISA M OAKES · 1999 to 2026
$18.9M
Theranostics of Photoreceptor-RPE-Choroid Neurovascular Unit in Mouse Models of Eye DiseasesR01EY026556 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Robert J Zawadzki · 2017 to 2026
$4.1M
Structure and Function of the Chorioretinal Complex in Age-Related Macular DegeneR01EY024239 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI WERNER, JOHN S · 2014 to 2018
$2.4M
Properties of Photoreceptors and Muller Cells Investigated with AO-OCTR00EY026068 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JONNAL, RAVI S. · 2018 to 2020
$739k
Properties of photoreceptors and Muller cells investigated with AO-OCTK99EY026068 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JONNAL, RAVI S. · 2016 to 2017
$196k
NEI NIH HHS K99 EY026068NEI NIH HHS P30 EY012576NEI NIH HHS R00 EY026068NEI NIH HHS R01 EY024239NEI NIH HHS R01 EY026556
6 · The paper itself

Abstract

In retinal raster imaging modalities, fixational eye movements manifest as image warp, where the relative positions of the beam and retina change during the acquisition of single frames. To remove warp artifacts, strip-based registration methods-in which fast-axis strips from target images are registered to a reference frame-have been applied in adaptive optics (AO) scanning light ophthalmoscopy (SLO) and optical coherence tomography (OCT). This approach has enabled object tracking and frame averaging, and methods have been described to automatically select reference frames with minimal motion. However, inconspicuous motion artifacts may persist in reference frames and propagate themselves throughout the processes of registration, tracking, and averaging. Here we test a previously proposed method for removing movement artifacts in reference frames, using biases in stripwise cross-correlation statistics. We applied the method to synthetic retinal images with simulated eye motion artifacts as well as real AO-SLO images of the cone mosaic and volumetric AO-OCT images, both affected by eye motion. In the case of synthetic images, the method was validated by direct comparison with motion-free versions of the images. In the case of real AO images, performance was validated by comparing the correlation of uncorrected images with that of corrected images, by quantifying the effect of motion artifacts on the image power spectra, and by qualitative examination of AO-OCT B-scans and en face projections. In all cases, the proposed method reduced motion artifacts and produced more faithful images of the retina.

Indexed as

Image Processing, Computer-AssistedMotionOptics and PhotonicsAlgorithmsArtifactsComputer SimulationEyeHumansOphthalmoscopy

Identifiers

PMID30359401
PMCPMC6201912
OpenAlexW2898558634

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.