Evidence map›Paper›PMID 30359249›Full record

ArticleBMC cancer2018

Long-term mortality among women with epithelial ovarian cancer: a population-based study in British Columbia, Canada.

Nimisha Arora, Aline Talhouk, Jessica N McAlpine, Michael R Law, Gillian E Hanley

Registry-linked trialAbstract read
In one paragraph

Article in BMC cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06253559 (Clinical and Pathological Characteristics of Women With Ovarian Cancers, A National, Retrospective Cross-Sectional Study in Syria During the War), which is not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06253559 completednot on this map

Clinical and Pathological Characteristics of Women With Ovarian Cancers, A National, Retrospective Cross-Sectional Study in Syria During the War

TypeobservationalSponsorLatakia UniversityRan2017 to 2023Enrolled531ConditionsOvarian Cancer
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  20. CD133 Act as an Essential Marker in Ovarian Carcinogenesis.Asian Pacific journal of cancer prevention : APJCP · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nimisha AroraDepartment of Obstetrics & Gynecology, University of British Columbia, Vancouver, BC, Canada.
Aline TalhoukDepartment of Obstetrics & Gynecology, University of British Columbia, Vancouver, BC, Canada.
Jessica N McAlpineDepartment of Obstetrics & Gynecology, University of British Columbia, Vancouver, BC, Canada.
Michael R LawCentre for Health Services and Policy Research, School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada.
Gillian E HanleyDepartment of Obstetrics & Gynecology, University of British Columbia, Vancouver, BC, Canada. Gillian.hanley@vch.ca.ORCID http://orcid.org/0000-0001-9594-0545

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAmong women with epithelial ovarian cancer (EOC), histotype is one of the major prognostic factors. However, few data are available on histotype- specific survival and mortality estimates among these patients. We therefore examined survival and causes of death among women with EOC by histotype.

methodsA population- based cohort including all ovarian cancer patients diagnosed in British Columbia (BC) between 1990 and 2014 was built using population-based administrative datasets. We compared causes of death within histotypes, by age at diagnosis, BRCA status, and time since diagnosis.

resultsA total of 6975 women were identified as having been diagnosed with EOC between 1990 and 2014 in BC. The most common cause of death among these women was ovarian cancer until 10 years post diagnosis when other causes surpassed ovarian cancer as the leading cause of death. Among women with serous EOCs, ovarian cancer was the leading cause of death 12 years after diagnosis, whereas ovarian cancer was the leading cause of death for 8 years among women with non- serous EOCs. Among women with serous EOCs, ovarian cancer was the leading cause of death for 12 years among younger women (< 60 years of age) compared to 8 years among women > = 60 years of age, and those with BRCA mutations were more likely to die from ovarian cancer than those without a BRCA mutation.

conclusionsWithin 10 years from diagnosis, ovarian cancer is the leading cause of death among women diagnosed with EOC.

Indexed as

AdultAgedAged, 80 and overBritish ColumbiaCarcinoma, Ovarian EpithelialFemaleHumansMiddle AgedMortalityPopulation SurveillanceSEER ProgramYoung AdultHistotypeMortalityOvarian CancerSurvival

Identifiers

PMID30359249
PMCPMC6202883

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.