ArticleLymphatic research and biology2018
Development and Validation of the Lymphedema Symptom Intensity and Distress Survey-Lower Limb.
Article in Lymphatic research and biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Patient-Reported Outcome Measures in Lymphedema: A Systematic Review and COSMIN Analysis.Annals of surgical oncology · 2021Pooled it
- Effects of Intermittent Pneumatic Compression on Lower Limb Lymphedema in Patients with Type 2 Diabetes Mellitus: A Pilot Randomized Controlled Trial.Medicina (Kaunas, Lithuania) · 2021Trial
- A Prospective Study of the Impact of Lymphatic Venous Anastomosis as a Treatment for Lymphedema.Plastic and reconstructive surgery. Global open · 2025Article
- Advances in etiology, pathophysiology, diagnosis, and management of lymphedema: a comprehensive review.Frontiers in medicine · 2025Review
- Acceptance of disability, coping style, perceived social support and quality of life among patients with chronic lymphedema: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Lymphedema Symptom Intensity and Distress Surveys-Truncal and Head and Neck, Version 2.0.Lymphatic research and biology · 2021Article
- Patient-Reported Outcome Measures With Secondary Lower Limb Lymphedemas: A Systematic Review.Journal of the advanced practitioner in oncology · 2021Review
- Standardization of lower extremity quantitative lymphedema measurements and associated patient-reported outcomes in gynecologic cancers.Gynecologic oncology · 2021Review
- Surgical Approach to Lymphedema Reduction.Current oncology reports · 2020Review
- A Comparison of Symptoms Among Patients with Head and Neck or Truncal Lymphedema and Normal Controls.Lymphatic research and biology · 2019Article
- Comparison of Staging Systems to Assess Lymphedema Caused by Cancer Therapies, Lymphatic Filariasis, and Podoconiosis.Lymphatic research and biology · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundLymphedema is a chronic, incurable condition that occurs most commonly in lower limbs (legs and feet). Increased morbidity is seen with this form of lymphedema, but there are few studies and even fewer tools intended to assess symptom burden in patients impacted by this condition. A questionnaire, the Lymphedema Symptom Intensity and Distress Survey-Lower Limb (LSIDS-L), was developed to fill this gap. The measure is composed of several clusters of symptoms thought to characterize lower limb lymphedema. The initial work was conducted to propose and assess the face validity of the clusters. Subsequently, work was undertaken to empirically evaluate the presence of the symptom clusters, assess the reliability of the cluster scores, and evaluate the validity of the scores by studying associations with other valid measures. METHODS AND
resultsDuring the initial work, the LSIDS-L was tested with lower limb lymphedema patients only, and in the subsequent work the LSIDS-L and valid measures were administered to patients with no lymphedema and with lower limb lymphedema. A total of 388 volunteers participated, 111 of whom indicated no diagnosis of lymphedema, and 277 indicated a diagnosis of lower limb lymphedema. Cluster analysis resulted in the exclusion of 5 items, yielding 8 clusters with a total of 31 items. Cluster scores demonstrated acceptable internal consistency, distinguished nonlymphedema patients from lower lymphedema patients, and demonstrated expected convergent and divergent validity with other valid measures.
conclusionThe LSIDS-L is a valid tool for detecting and quantifying symptom burden in patients with lower limb lymphedema.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.