Evidence map›Paper›PMID 30359090›Full record

ArticleAmerican journal of respiratory and critical care medicine2019

Alpha-1 Antitrypsin Deficiency as an Incidental Finding in Clinical Genetic Testing.

Craig P Hersh, Edward J Campbell, Lauren R Scott, Benjamin A Raby

Abstract readCase ReportsLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Alpha-1 Antitrypsin Deficiency: a Rare Disease?Current allergy and asthma reports · 2020
    Review
  5. The Effects of RareAmerican journal of respiratory and critical care medicine · 2020
    Article
  6. Pharmacogenomics of chronic obstructive pulmonary disease.Expert review of respiratory medicine · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Craig P Hersh1 Brigham and Women's Hospital Boston, Massachusetts.ORCID 0000-0002-1342-4334
Edward J Campbell2 HerediLab, Inc. Salt Lake City, Utah and.
Lauren R Scott2 HerediLab, Inc. Salt Lake City, Utah and.
Benjamin A Raby1 Brigham and Women's Hospital Boston, Massachusetts.ORCID 0000-0003-2206-5748

Funding

SYSTEMS GENOMICS OF THE ASTHMA-COPD OVERLAP SYNDROMER01HL130512 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI HERSH, CRAIG P · 2016 to 2019
$3.5M
INTEGRATIVE GENOMICS OF CLINICAL SUBTYPES IN COPDGENER01HL125583 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI HERSH, CRAIG P · 2015 to 2018
$3.5M
NHLBI NIH HHS R01 HL125583NHLBI NIH HHS R01 HL130512
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Incidental FindingsAdultalpha 1-Antitrypsinalpha 1-Antitrypsin DeficiencyFemaleGenetic TestingHumansMaleMiddle Agedalpha 1-Antitrypsin

Identifiers

PMID30359090
PMCPMC6353005

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.