ArticlePsychological assessment2019
Do we need an irritable subtype of ADHD? Replication and extension of a promising temperament profile approach to ADHD subtyping.
Article in Psychological assessment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 1 of them a synthesis that pooled it.
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Who cites it
90 citing papers in PubMed, 1 synthesis or guideline pooled it, 125 citations in OpenAlex.
- Annual Research Review: What processes are dysregulated among emotionally dysregulated youth? - a systematic review.Journal of child psychology and psychiatry, and allied disciplines · 2025Pooled it
- Associations between ADHD Symptoms and Psychiatric Symptoms in Children: Effects of Functional Impairment and Temperament.Journal of attention disorders · 2026Article
- Important Mechanisms in the Development of Anxiety in Children with ADHD: The Role of Associated Features of ADHD and Interpersonal Functioning.Child psychiatry and human development · 2026Review
- Reproducible Temperament Profiles in Adolescents With Attention-Deficit/Hyperactivity Disorder Prospectively Predict Clinical Outcomes.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- Neurocognitive and Temperament Predictors of Changes in Child and Adolescent Suicidal Thoughts and Behaviors for Youths With and Without Attention-Deficit/Hyperactivity Disorder.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- Emotional Profiles in Adolescents With ADHD: A Person-Centered Analysis of Emotion Regulation, Resilience, and Internalizing Symptoms.Alpha psychiatry · 2026Article
- Emotion Dysregulation in Children with ADHD: Irritability is Associated with EEG-Measured Frontal Alpha Asymmetry in Response to Emotional Stimuli.Research on child and adolescent psychopathology · 2026Article
- How Does Adult Temperament Relate to ADHD Symptom Domains? Testing the Dual-Pathway Model.Journal of attention disorders · 2026Article
- Mapping phenotypic and genetic relationships among irritability, depression and ADHD in adolescence using network analysis.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
- The Evolving ADHD Phenotype in the Externalizing Context.The American journal of psychiatry · 2026Review
- Transdiagnostic Behavioral Phenotypes and Comorbid Gastrointestinal Symptoms in Neurodevelopmental Disorders: An Exploratory Study.Autism research : official journal of the International Society for Autism Research · 2026Article
- Reactivity and regulation of negative and positive emotions in child- and adolescent diagnostic and trait-level ADHD: a cross-sectional study.BMC psychiatry · 2025Article
- Distinct neuroimaging subtypes of ADHD among adolescents based on semi-supervised learning.Translational psychiatry · 2025Article
- Beyond Negative Emotions: Positive Emotion Reactivity and Social Impairments in Children with and without Elevated ADHD Symptoms.Research on child and adolescent psychopathology · 2025Article
- Differences in Resting-State Functional Connectivity of Temperament-Based Profiles Among Youths With Attention-Deficit/Hyperactivity Disorder in the Adolescent Brain Cognitive Development Study.Clinical psychological science : a journal of the Association for Psychological Science · 2025Article
- Not just old wine in new bottles: Polygenic liability for ADHD is associated with electrophysiological affective-motivational processing beyond anxiety, depression, and ODD.Translational psychiatry · 2025Article
- Clustering Analysis of Cognitive Profiles of Clinical Groups Using the CAS: An Examination of Japanese Clinical Populations.Journal of Intelligence · 2025Article
- Reproducible structure with measurement invariance for the Parent-Report Early Adolescent Temperament Questionnaire: Findings from three independent samples.Psychological assessment · 2025Article
- Behavioral and neurofunctional profiles of delay aversion in children with attention-deficit hyperactivity disorder.Translational psychiatry · 2025Article
- Article
30 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Attention deficit hyperactivity disorder (ADHD) is emblematic of unresolved heterogeneity in psychiatric disorders-the variation in biological, clinical, and psychological correlates that impedes progress on etiology. One approach to this problem is to characterize subgroups using measures rooted in biological or psychological theory, consistent with the National Institute of Mental Health's research domain criteria initiative. Within ADHD, a promising application involves using emotion trait profiles that can address the role of irritability as a complicating feature for ADHD. Here, a new sample of 186 children with ADHD was evaluated using community detection analysis to determine if meaningful subprofiles existed and if they replicated those previously identified. The new sample and a prior sample were pooled for evaluation of (a) method dependence, (b) longitudinal assessment of the stability of classifications, and (c) clinical prediction 2 years later. Three temperament profiles were confirmed within the ADHD group: one with normative emotional functioning ("mild"), one with high surgency ("surgent"), and one with high negative affect ("irritable"). Profiles were similar across statistical clustering approaches. The irritable group had the highest external validity: It was moderately stable over time and it enhanced prospective prediction of clinical outcomes beyond standard baseline indicators. The irritable group was not reducible to ADHD + oppositional defiant disorder, ADHD + disruptive mood dysregulation disorder, or other patterns of comorbidity. Among the negative affect domains studied, trait proneness to anger uniquely contributed to clinical prediction. Results extend our understanding of chronic irritability in psychiatric disorders and provide prospects for a fresh approach to assessing ADHD heterogeneity focused on the distinction between ADHD with and without anger/irritability. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.