ArticleEnvironmental science & technology2018
Long-Term in Situ Reduction in Soil Lead Bioavailability Measured in a Mouse Model.
Article in Environmental science & technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- An integrated experimental and modeling approach to understand pyromorphite solubility.Chemosphere · 2025Article
- Lead Speciation, Bioaccessibility, and Sources for a Contaminated Subset of House Dust and Soils Collected from Similar United States Residences.Environmental science & technology · 2024Article
- Remediation options to reduce bioaccessible and bioavailable lead and arsenic at a smelter impacted site - consideration of treatment efficacy.Environmental pollution (Barking, Essex : 1987) · 2024Article
- Potassium jarosite seeding of soils decreases lead and arsenic bioaccessibility: A path toward concomitant remediation.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Microbial functionalities and immobilization of environmental lead: Biogeochemical and molecular mechanisms and implications for bioremediation.Journal of hazardous materials · 2023Review
- Dietary lead modulates the mouse intestinal microbiome: Subacute exposure to lead acetate and lead contaminated soil.Ecotoxicology and environmental safety · 2023Article
- Ca Minerals and Oral Bioavailability of Pb, Cd, and As from Indoor Dust in Mice: Mechanisms and Health Implications.Environmental health perspectives · 2022Article
- Successful Conversion of Pb-Contaminated Soils to Low-Bioaccessibility Plumbojarosite Using Potassium-Jarosite at Ambient Temperature.Environmental science & technology · 2022Article
- Ingestion of remediated lead-contaminated soils affects the fecal microbiome of mice.The Science of the total environment · 2022Article
- Plumbojarosite Remediation of Soil Affects Lead Speciation and Elemental Interactions in Soil and in Mice Tissues.Environmental science & technology · 2021Article
- Improving the predictive value of bioaccessibility assays and their use to provide mechanistic insights into bioavailability for toxic metals/metalloids - A research prospectus.Journal of toxicology and environmental health. Part B, Critical reviews · 2021Review
- Plumbojarosite formation in contaminated soil to mitigate childhood exposure to lead, arsenic and antimony.Journal of hazardous materials · 2021Article
- Lead (Pb) concentrations and speciation in residential soils from an urban community impacted by multiple legacy sources.Journal of hazardous materials · 2021Article
- Bioavailable soil Pb minimized by in situ transformation to plumbojarosite.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- High Lead Bioavailability of Indoor Dust Contaminated with Paint Lead Species.Environmental science & technology · 2021Article
- Lead speciation, bioaccessibility and source attribution in Missouri's Big River watershed.Applied geochemistry : journal of the International Association of Geochemistry and Cosmochemistry · 2020Article
- Dietary Lead and Phosphate Interactions Affect Oral Bioavailability of Soil Lead in the Mouse.Environmental science & technology · 2019Article
- Relationship between Pb relative bioavailability and bioaccessibility in phosphate amended soil: Uncertainty associated with predicting Pb immobilization efficacy using in vitro assays.Environment international · 2019Article
- Dynamics of Lead Bioavailability and Speciation in Indoor Dust and X-ray Spectroscopic Investigation of the Link between Ingestion and Inhalation Pathways.Environmental science & technology · 2019Article
- Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Effects of different treatments on the bioavailability of lead (Pb) in soil from a smelter emission contaminated site in Joplin, Missouri, were evaluated in a mouse model. Similar estimates of relative bioavailability for Pb in untreated or treated soil were obtained in mice and in the well-established juvenile swine model. In the mouse model, treatments that used phosphate (phosphoric acid or triple superphosphate) combined with iron oxide or biosolids compost significantly reduced soil Pb bioavailability. Notably, effects of these remediation procedures were persistent, given that up to 16 years had elapsed between soil treatment and sample collection. Remediation of soils was associated with changes in Pb species present in soil. Differences in Pb species in ingested soil and in feces from treated mice indicated that changes in Pb speciation occurred during transit through the gastrointestinal tract. Use of the mouse model facilitates evaluation of remediation procedures and allows monitoring of the performance of procedures under laboratory and field conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.