ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2019
The Relationship Between Cognitive Impairment and Upper Extremity Function in Older Primary Care Patients.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Impact of action observation therapy on motor and cognitive outcomes in older adults with mild cognitive impairment: a randomized controlled study.Frontiers in public health · 2025Trial
- The Virtual Kitchen Challenge-Version 2: Validation of a Digital Assessment of Everyday Function in Older Adults.JMIR aging · 2026Article
- More than pain and physical limitation: the declined cognitive performance associated with rotator cuff injuries.Journal of orthopaedic surgery and research · 2025Article
- Detection of mild cognitive impairment using a virtual reality-based stroop task: a cross-sectional study of embodied behavioral markers.Journal of neuroengineering and rehabilitation · 2025Observational
- Discriminant Power of Smartphone-Derived Keystroke Dynamics for Mild Cognitive Impairment Compared to a Neuropsychological Screening Test: Cross-Sectional Study.Journal of medical Internet research · 2024Article
- Investigating the associations between upper limb motor function and cognitive impairment: a scoping review.GeroScience · 2023Article
- The assessment of executive functions to test the integrity of the nigrostriatal network: A pilot study.Frontiers in psychology · 2023Article
- Developments in scalable strategies for detecting early markers of cognitive decline.Translational psychiatry · 2022Review
- The Neglected Factor in the Relationship between Executive Functioning and Obesity: The Role of Motor Control.Healthcare (Basel, Switzerland) · 2022Article
- Detection of Mild Cognitive Impairment Through Natural Language and Touchscreen Typing Processing.Frontiers in digital health · 2020Article
- Heterogeneity of Informant-Reported Functional Performance in Mild Cognitive Impairment: A Latent Profile Analysis of the Functional Activities Questionnaire.Journal of Alzheimer's disease : JAD · 2019Article
- Associations between Cognition and Hand Function in Older People Diagnosed with Mild Cognitive Impairment or Dementia.Dementia and geriatric cognitive disorders extraArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundIndividuals with mild cognitive impairment (MCI), often a precursor to dementia, experience limitations in completing daily activities. These limitations are particularly important to understand, as they predict risk for dementia. Relations between functional changes and both cognitive decline and upper extremity motor impairments have been reported, but the contribution of motor function to relations between cognitive function and functional independence remains poorly understood. We examined the relationship between cognition and upper extremity activities, and whether this relation was mediated by motor function.
methodsA total of 430 community-dwelling primary care patients aged at least 65 years from the Boston Rehabilitative Impairment Study of the Elderly completed self-report measures of upper extremity function, tests of neuromuscular attributes to measure motor function (reaction time, pronosupination of the hands), and neuropsychological measures. Participants were classified based on cognitive performance into groups: MCI and without MCI, with MCI further classified by cognitive subtype. Regression and mediation analyses examined group differences and relations between cognitive function, upper extremity function, and neuromuscular attributes.
resultsMCI participants demonstrated poorer neuromuscular attributes and self-reported upper extremity function, and neuromuscular attributes significantly mediated positive relations between cognitive status and self-reported upper extremity function. Poorer self-reported upper extremity function was most prominent for groups with executive dysfunction.
conclusionsTogether with previous research, results suggest that the relationship between cognitive function, motor function, and functional activities is not confined to mobility tasks but universally related to body systems and functional activities. These findings inform new approaches for dementia risk screening and rehabilitative care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.