ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2019
Vision Impairment and Cognitive Outcomes in Older Adults: The Health ABC Study.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 69 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
69 citing papers in PubMed, 2 syntheses or guidelines pooled it, 123 citations in OpenAlex.
- Pooled it
- The Bidirectional Relationship between Vision and Cognition: A Systematic Review and Meta-analysis.Ophthalmology · 2021Pooled it
- Sensory Difficulty, Social and Physical Activity, and Dementia Risk Among Older Adults.Journal of aging and health · 2026Article
- Sensory impairment, loneliness, and the emergence of physical-psychological-cognitive multimorbidity: a cross-national cohort study in China, the United States, and England.International journal for equity in health · 2026Article
- A sensorimotor function construct to assess mild cognitive impairment risk.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Sensory impairments and cognitive impairment among Mexican American older adults: nativity differences.Aging & mental health · 2026Article
- Relationship Between Visual Acuity and Cognitive Functions in Older Adults With Visual Impairment: The Mediating Role of Frailty.Brain and behavior · 2025Article
- Relationship of Visual Impairment and Poor Mobility With Mortality.Journal of the American Geriatrics Society · 2025Article
- Human Guide Training to Improve Hospital Accessibility for Patients Who Are Blind: Needs Assessment and Pilot Process Evaluation.JMIR rehabilitation and assistive technologies · 2025Article
- Sensory impairment and dementia risk among older adults in rural South Africa.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Prevalence and Patient-Centered, Health-Related, and Economic Impact of Under-Corrected Refractive Error in Community-Based Older Singaporean Adults: A Population-Based Study.Investigative ophthalmology & visual science · 2025Article
- Moderate Impairment in Binocular Contrast Sensitivity Predicts Faster Mobility Decline in Cognitively Unimpaired Older Adults.Journal of the American Geriatrics Society · 2025Article
- Visual Impairment and Cognitive Function in Aging Adults: Sex and Age Differences in Mediating Effect of Social Isolation and Depression.American journal of ophthalmology · 2025Article
- The association between stereoscopic vision and cognitive function on community-dwelling older adults: a cross-sectional study.BMC geriatrics · 2025Article
- Relationship of Multiple Sensory Impairments With Physical Performance in Older Adults in the Study of Muscle, Mobility and Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Visual impairment predicts greater declines in physical performance over time: the Health, Aging and Body Composition Study.BMC geriatrics · 2025Article
- Adaptation and validation of the modified Egyptian Arabic version of Addenbrooke's Cognitive Examination III (VI-ACE-III) for assessing cognitive impairment in visually impaired elderly.BMC geriatrics · 2025Article
- Sensory impairments associated with cognitive impairment among older adults in China: A community-based, 10-year prospective cohort study.Journal of global health · 2024Article
- Article
- Social engagement and cognitive impairment among nursing home residents: The role of sensory impairment.Archives of gerontology and geriatrics · 2024Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundAn association between visual impairment and cognitive outcomes has been documented, but there is limited research examining this relationship using multiple measures of vision.
methodsParticipants included non-demented individuals in Year 3 of the Visual impairment was assessed using visual acuity, contrast sensitivity, and stereo acuity. Cognitive function was defined using the digit symbol test and the Modified Mini-Mental State Examination (3MS). Incident cognitive impairment was defined as a 3MS score <80 or a decline >5 points following Year 3. Linear mixed effects models examined longitudinal associations adjusting for year, age, sex, race, education, smoking, depression, diabetes, study site, as well as interaction terms between the vision parameters and years in study, between baseline age and years in study, and quadratic terms of baseline age and years in study. Discrete Cox regression models examined the risk of incident cognitive impairment.
resultsAnalyses included 2,444 participants (mean age = 74). Visual acuity, contrast sensitivity, and stereo acuity impairments were not associated with statistically significant changes in annual digit symbol test scores over 7 years of follow-up, as compared to those without these impairments. However, visual acuity, contrast sensitivity, and stereo acuity impairments were associated with greater declines in annual 3MS scores over 9 years. Participants with impaired visual acuity, contrast sensitivity, and stereo acuity had a greater risk of incident cognitive impairment.
conclusionsOur results suggest that visual acuity, contrast sensitivity, and stereo acuity impairments may be risk factors for cognitive decline.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.