Evidence map›Paper›PMID 30358241›Full record

ArticleThe Journal of clinical psychiatry2018

Circadian Pattern of Deaths Due to Suicide in Intoxicated Alcohol-Dependent Individuals.

Subhajit Chakravorty, Rachel V Smith, Michael L Perlis, Michael A Grandner, Henry R Kranzler

Open access · greenAbstract read
In one paragraph

Article in The Journal of clinical psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Subhajit ChakravortyCorporal Michael J. Crescenz VA Medical Center, Perelman School of Medicine, MIRECC, 2nd Fl, Postal Code 116, 3900 Woodland Ave, Philadelphia, PA 19104. subhajit.chakravorty@uphs.upenn.edu.
Rachel V SmithUniversity of Louisville School of Nursing, Louisville, Kentucky, USA.
Michael L PerlisPerelman School of Medicine of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Michael A GrandnerUniversity of Arizona College of Medicine, Tucson, Arizona, USA.
Henry R KranzlerCorporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania, USA.
Philadelphia VA Medical Center · USUniversity of Arizona · USUniversity of Louisville · USUniversity of Pennsylvania · US

Funding

Sleep and Cardiometabolic Health Disparities at the US/Mexico Border: The Nogales Cardiometabolic Health and Sleep (NoCHeS) StudyR01MD011600 · NIMHD · UNIVERSITY OF ARIZONA · PI GRANDNER, MICHAEL A · 2018 to 2022
$4.1M
Pharmacogenetic Analysis of Topiramate Treatment of AUDR01AA023192 · NIAAA · UNIVERSITY OF PENNSYLVANIA · PI KRANZLER, HENRY RICHARD · 2014 to 2018
$2.7M
Prospective Assessment of The Etiology of Insomnia in Middle Aged & Elder AdultsR01AG041783 · NIA · UNIVERSITY OF PENNSYLVANIA · PI PERLIS, MICHAEL LLOYD · 2013 to 2016
$2.4M
2/2 Pharmacogenetic Treatment for AlcoholismR01AA021164 · NIAAA · UNIVERSITY OF PENNSYLVANIA · PI KRANZLER, HENRY RICHARD, PETTINATI, HELEN M · 2012 to 2016
$2.1M
Behavioral Sleep Medicine: Training in Sleep and AgingK24AG055602 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Michael Lloyd Perlis · 2017 to 2026
$1.6M
Cardiovascular and Metabolic Risk Factors Associated with Short Sleep DurationK23HL110216 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI GRANDNER, MICHAEL A · 2012 to 2016
$813k
Three Approaches to Maintenance Therapy for Chronic Insomnia in Older AdultsR56AG050620 · NIA · UNIVERSITY OF PENNSYLVANIA · PI PERLIS, MICHAEL LLOYD · 2016 to 2016
$805k
Sleep and Health in the Social EnvironmentR21ES022931 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI GRANDNER, MICHAEL A · 2012 to 2013
$436k
CSRD VA IK2 CX000855NHLBI NIH HHS K23 HL110216NIAAA NIH HHS R01 AA021164NIAAA NIH HHS R01 AA023192NIA NIH HHS K24 AG055602NIA NIH HHS R01 AG041783NIA NIH HHS R56 AG050620NIEHS NIH HHS R21 ES022931NIMHD NIH HHS R01 MD011600
6 · The paper itself

Abstract

objectiveAlcohol intoxication and dependence are risk factors for suicide, a leading cause of death in the United States. We examined the hours of peak and nadir in completed suicides over a 24-hour period among intoxicated, alcohol-dependent individuals. We also evaluated suicide-related factors associated with intoxication at different times of the day.

methodsWe analyzed cross-sectional data from the 2003-2010 National Violent Death Reporting System provided by 16 US states. In the primary database, the deceased individuals' alcohol-dependent status was classified as "yes" or "no or unknown." We restricted the analysis to alcohol-dependent individuals with alcohol level data available (N = 3,661). The primary outcome measure was the reported time of death. Secondary outcome measures were predisposing and injury-related factors. Individuals were classified on the basis of their blood alcohol level (BAL) as heavy drinking (BALH [≥ 80 mg/dL]) or non-heavy drinking (BALO [< 80 mg/dL]). The time of injury was divided into 1-hour bins, which were used to compute the incidence of suicide over 24 hours. We also evaluated the association between clinical factors and BALH for each of six 4-hour time periods beginning at 00:01 hours.

resultsThe majority (73.4%) of individuals showed evidence of alcohol consumption prior to committing suicide. BALH was observed in 60.7% of all individuals. Peak incidences in suicide were identified at 21:00 for BALH and 12:00 for BALO, with nadirs at 05:00 and 03:00 hours, respectively. In a multivariable analysis, between 20:01 and 00:00 hours, BALH was associated with more risk and protective factors than BALO.

conclusionsIdentifying critical times and associated risk factors for suicidal behavior may contribute to suicide prevention efforts in intoxicated alcohol-dependent individuals.

Indexed as

Blood Alcohol ContentAdultAlcoholic IntoxicationAlcoholismAnalysis of VarianceCircadian RhythmCross-Sectional StudiesDatabases, FactualFemaleFirearmsHumansIncidenceMaleMental DisordersMiddle AgedPopulation SurveillanceBlood Alcohol Content

Identifiers

PMID30358241
PMCPMC7486887
OpenAlexW2895899432

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.