Evidence map›Paper›PMID 30358025›Full record

ArticleDepression and anxiety2019

Incidence of mental health hospitalizations, treated self-harm, and emergency room visits following new anxiety disorder diagnoses in privately insured U.S. children.

Greta A Bushnell, Bradley N Gaynes, Scott N Compton, Stacie B Dusetzina, M Alan Brookhart, Til Stürmer

Abstract read
In one paragraph

Article in Depression and anxiety, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Comparative analysis of pediatric anxiety measures in clinical sample: evaluation of the PROMIS pediatric anxiety short forms.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Incident Substance Use Disorder Following Anxiety Disorder in Privately Insured Youth.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Greta A BushnellDepartment of Epidemiology, University of North Carolina at Chapel Hill Gillings School of Global Public Health, Chapel Hill, North Carolina.ORCID 0000-0002-4056-8405
Bradley N GaynesDepartment of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina.
Scott N ComptonDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina.
Stacie B DusetzinaDepartment of Health Policy, Vanderbilt University Medical Center, Nashville, Tennessee.
M Alan BrookhartDepartment of Epidemiology, University of North Carolina at Chapel Hill Gillings School of Global Public Health, Chapel Hill, North Carolina.
Til StürmerDepartment of Epidemiology, University of North Carolina at Chapel Hill Gillings School of Global Public Health, Chapel Hill, North Carolina.ORCID 0000-0002-9204-7177

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
North Carolina Translational & Clinical Sciences Institute (NC TraCS)UL1TR001111 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$43.9M
RESEARCH TRAINING PROGRAM IN PSYCHIATRIC EPIDEMIOLOGYT32MH013043 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Katherine M. Keyes · 1985 to 2026
$11.7M
Propensity Scores and Preventive Drug Use in the ElderlyR01AG023178 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI STURMER, TIL · 2005 to 2014
$2.7M
Methods for Estimating Sex Differences in Safety and Effectiveness of DrugsR01HL118255 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JONSSON FUNK, MICHELE LAURA · 2014 to 2017
$1.7M
PROMIS Validation in Prospective Population-based Prostate Cancer Research StudyR01CA174453 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHEN, RONALD, REEVE, BRYCE B · 2012 to 2016
$1.4M
Patterns of use, comparative effectiveness, and safety of rotavirus vaccinesR21HD080214 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BROOKHART, MAURICE ALAN · 2014 to 2015
$413k
Pediatric anxiety: Pharmacotherapy and psychotherapy utilization and serious adverse outcomesF31MH107085 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSHNELL, GRETA · 2015 to 2017
$60k
NCATS NIH HHS UL1 TR001111NCATS NIH HHS UL1 TR002489NCI NIH HHS R01 CA174453NHLBI NIH HHS R01 HL118255NIA NIH HHS R01 AG023178NICHD NIH HHS R21 HD080214NIMH NIH HHS F31 MH107085NIMH NIH HHS T32 MH013043
6 · The paper itself

Abstract

backgroundAnxiety disorders are one of the most common mental illnesses in children and associated with high healthcare utilization. We aimed to estimate 2-year cumulative incidence of mental health-related hospitalizations, treated self-harm, and emergency room (ER) visits in children newly diagnosed with anxiety disorders and, for context, in children without anxiety disorders.

methodsWe identified commercially insured treatment naïve children (3-17 years) with a new office-based anxiety disorder diagnosis (ICD-9-CM) from 2005-2014 in the MarketScan claims database. We followed children for up to 2 years after diagnosis for the first of each event: mental health-related hospitalization, inpatient, treated self-harm, and ER visits (any, anxiety-related, injury-related). Children without anxiety diagnoses were included as comparators, matched on age, sex, date, and region. We estimated cumulative incidence of each event using Kaplan-Meier analysis.

resultsFrom 2005-2014, we identified 198,450 children with a new anxiety diagnosis. One-year after anxiety diagnosis, 2.0% of children had a mental health-related hospitalization, 0.08% inpatient, treated self-harm, 1.4% anxiety-related ER visit, and 20% any ER visit; incidence was highest in older children with baseline comorbid depression. One-year cumulative incidence of each event was lower in the comparison cohort without anxiety (e.g., mental health-related hospitalizations = 0.5%, treated self-harm = 0.01%, and ER visits = 13%).

conclusionsGiven the prevalence of anxiety disorders, 2-year incidence estimates translate to a significant number of children experiencing each event. Our findings offer caregivers, providers, and patients information to better understand the burden of anxiety disorders and can help anticipate healthcare utilization and inform efforts to prevent these serious events.

Indexed as

AdolescentAnxietyAnxiety DisordersChildCohort StudiesComorbidityDepressionEmergency Service, HospitalFemaleHospitalizationHumansIncidenceInsurance, HealthMaleMental HealthPrevalenceanxiety disorderschildemergency servicehealthcare utilizationhospitalizationincidenceself-injurious behavior

Identifiers

PMID30358025
PMCPMC6488302

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.