ReviewMovement disorders : official journal of the Movement Disorder Society2018
An update on adaptive deep brain stimulation in Parkinson's disease.
Review in Movement disorders : official journal of the Movement Disorder Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Adaptive deep brain stimulation for Parkinson's disease: looking back at the past decade on motor outcomes.Journal of neurology · 2023Pooled it
- Electrical stimulation of the nucleus basalis of meynert: a systematic review of preclinical and clinical data.Scientific reports · 2021Pooled it
- Deep brain stimulation of the brainstem.Brain : a journal of neurology · 2021Pooled it
- Consensus Statement on High-Intensity Focused Ultrasound for Functional Neurosurgery in Switzerland.Frontiers in neurology · 2021Pooled it
- Adaptive versus conventional deep brain stimulation for bradykinesia in Parkinson's disease: a comparative effectiveness analysis.Acta neurologica Belgica · 2026Review
- Burst deep brain stimulation for Parkinson's disease: A systematic review of efficacy and safety.Journal of Parkinson's disease · 2026Review
- Local Field Aperiodic Spectral Power Modulated by Deep Brain Stimulation in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- Continuous Accelerometry-Based Tremor Detection During Daily Living.Sensors (Basel, Switzerland) · 2026Article
- Adaptive Deep Brain Stimulation Benefits: Younger Patients with Persistent Wearing-off Symptoms.Movement disorders clinical practice · 2026Article
- Excessive daytime sleepiness in parkinsonism is associated with cortical and basal ganglia beta oscillatory activity.Communications biology · 2026Article
- An Improved Beta Burst Extraction for Chip-Based Deep Brain Stimulation With Real-Time Model Updating.IEEE open journal of engineering in medicine and biology · 2026Article
- The application of AI-driven digital phenotyping and interventions in neuropsychiatric disorders.Frontiers in psychiatry · 2026Review
- Shaping the Future of Psychiatric Neurosurgery: From Connectomic Precision to Technological Integration.Brain sciences · 2025Review
- AI-Driven Advances in Parkinson's Disease Neurosurgery: Enhancing Patient Selection, Trial Efficiency, and Therapeutic Outcomes.Brain sciences · 2025Review
- Comprehensive clinical scale-based machine learning model for predicting subthalamic nucleus deep brain stimulation outcomes in Parkinson's disease.Neurosurgical review · 2025Article
- N2GNet tracks gait performance from subthalamic neural signals in Parkinson's disease.NPJ digital medicine · 2025Article
- Evaluation of the therapeutic effect of adaptive deep brain stimulation on motor symptoms and sleep disturbances in Parkinson's disease and construction of a response prediction model.Frontiers in neurology · 2025Article
- Revealing connectivity patterns of deep brain stimulation efficacy in Parkinson's disease.Scientific reports · 2024Article
- Survey of common deep brain stimulation programming practices by experts in Parkinson's Disease.Journal of neurology · 2024Article
- Genomics of severe and treatment-resistant obsessive-compulsive disorder treated with deep brain stimulation: A preliminary investigation.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2024Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Advancing conventional open-loop DBS as a therapy for PD is crucial for overcoming important issues such as the delicate balance between beneficial and adverse effects and limited battery longevity that are currently associated with treatment. Closed-loop or adaptive DBS aims to overcome these limitations by real-time adjustment of stimulation parameters based on continuous feedback input signals that are representative of the patient's clinical state. The focus of this update is to discuss the most recent developments regarding potential input signals and possible stimulation parameter modulation for adaptive DBS in PD. Potential input signals for adaptive DBS include basal ganglia local field potentials, cortical recordings (electrocorticography), wearable sensors, and eHealth and mHealth devices. Furthermore, adaptive DBS can be applied with different approaches of stimulation parameter modulation, the feasibility of which can be adapted depending on specific PD phenotypes. Implementation of technological developments like machine learning show potential in the design of such approaches; however, energy consumption deserves further attention. Furthermore, we discuss future considerations regarding the clinical implementation of adaptive DBS in PD. © 2018 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.